Machine learning and clinical epigenetics: a review of challenges for diagnosis and classification

S Rauschert, K Raubenheimer, PE Melton… - Clinical epigenetics, 2020 - Springer
Background Machine learning is a sub-field of artificial intelligence, which utilises large data
sets to make predictions for future events. Although most algorithms used in machine …

[HTML][HTML] Epigenetic and long-term effects of nicotine on biology, behavior, and health

TJ Gould - Pharmacological Research, 2023 - Elsevier
Tobacco and nicotine use are associated with disease susceptibility and progression.
Health challenges associated with nicotine and smoking include developmental delays …

Neurobiology of addiction

GF Koob, DB Kandel, RD Baler, ND Volkow - Tasman's Psychiatry, 2023 - Springer
Substance use disorders (SUDs) manifest as chronic relapsing disorders, characterized by
compulsive drug taking despite serious adverse consequences, the loss of control over …

Epigenetics of pregnancy: looking beyond the DNA code

D Zuccarello, U Sorrentino, V Brasson, L Marin… - Journal of assisted …, 2022 - Springer
Epigenetics is the branch of genetics that studies the different mechanisms that influence
gene expression without direct modification of the DNA sequence. An ever-increasing …

Recent findings in the genetics and epigenetics of asthma and allergy

M Kabesch, J Tost - Seminars in immunopathology, 2020 - Springer
In asthma and allergy genetics, a trend towards a few main topics developed over the last 2
years. First, a number of studies have been published recently which focus on overlapping …

Quality of life and a surveillant endocannabinoid system

RA de Melo Reis, AR Isaac, HR Freitas… - Frontiers in …, 2021 - frontiersin.org
The endocannabinoid system (ECS) is an important brain modulatory network. ECS
regulates brain homeostasis throughout development, from progenitor fate decision to neuro …

Epigenetic alterations of maternal tobacco smoking during pregnancy: a narrative review

A Nakamura, O François, J Lepeule - International Journal of …, 2021 - mdpi.com
In utero exposure to maternal tobacco smoking is the leading cause of birth complications in
addition to being associated with later impairment in child's development. Epigenetic …

[PDF][PDF] Epigenetics and the exposome: DNA methylation as a proxy for health impacts of prenatal environmental exposures

ML Colwell, C Townsel, RL Petroff, JM Goodrich… - …, 2023 - academic.oup.com
The accumulation of everyday exposures can impact health across the life course, but our
understanding of such exposures is impeded by our ability to delineate the relationship …

Epigenetics as a biomarker for early-life environmental exposure

R Schrott, A Song, C Ladd-Acosta - Current environmental health reports, 2022 - Springer
Abstract Purpose of Review There is interest in evaluating the developmental origins of
health and disease (DOHaD) which emphasizes the role of prenatal and early-life …

DNA methylation patterns within whole blood of adolescents born from assisted reproductive technology are not different from adolescents born from natural …

B Penova-Veselinovic, PE Melton… - Human …, 2021 - academic.oup.com
STUDY QUESTION Do the epigenome-wide DNA methylation profiles of adolescents born
from ART differ from the epigenome of naturally conceived counterparts? SUMMARY …