The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception

MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2013 - Elsevier
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …

2014 Update of the Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception

MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2015 - Elsevier
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …

[HTML][HTML] Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity

S Palmqvist, M Schöll, O Strandberg, N Mattsson… - Nature …, 2017 - nature.com
It is not known exactly where amyloid-β (Aβ) fibrils begin to accumulate in individuals with
Alzheimer's disease (AD). Recently, we showed that abnormal levels of Aβ42 in …

Longitudinal tau accumulation and atrophy in aging and alzheimer disease

TM Harrison, R La Joie, A Maass, SL Baker… - Annals of …, 2019 - Wiley Online Library
Objective To determine the rate of tau accumulation in healthy older adults (OA) and patients
with Alzheimer disease (AD), as well as the relationship of tau accumulation to cortical …

[HTML][HTML] Reactive astrogliosis is associated with higher cerebral glucose consumption in the early Alzheimer's continuum

G Salvadó, M Milà-Alomà, M Shekari, NJ Ashton… - European journal of …, 2022 - Springer
Purpose Glial activation is one of the earliest mechanisms to be altered in Alzheimer's
disease (AD). Glial fibrillary acidic protein (GFAP) relates to reactive astrogliosis and can be …

[HTML][HTML] Pilot study of repeated blood-brain barrier disruption in patients with mild Alzheimer's disease with an implantable ultrasound device

S Epelbaum, N Burgos, M Canney, D Matthews… - Alzheimer's Research & …, 2022 - Springer
Background Temporary disruption of the blood-brain barrier (BBB) using pulsed ultrasound
leads to the clearance of both amyloid and tau from the brain, increased neurogenesis, and …

Brain alterations in the early Alzheimer's continuum with amyloid-β, tau, glial and neurodegeneration CSF markers

G Salvadó, M Shekari, C Falcon, G Operto… - Brain …, 2022 - academic.oup.com
Higher grey matter volumes/cortical thickness and fluorodeoxyglucose uptake have been
consistently found in cognitively unimpaired individuals with abnormal Alzheimer's disease …

[HTML][HTML] A systematic review of longitudinal studies which measure Alzheimer's disease biomarkers

E Lawrence, C Vegvari, A Ower… - Journal of …, 2017 - content.iospress.com
Alzheimer's disease (AD) is a progressive and fatal neurodegenerative disease, with no
effective treatment or cure. A gold standard therapy would be treatment to slow or halt …

Subclinical atherosclerosis and brain metabolism in middle-aged individuals: the PESA study

M Cortes-Canteli, JD Gispert, G Salvadó… - Journal of the American …, 2021 - jacc.org
Background Atherosclerosis has been linked to cognitive decline in late life; however, the
impact of cardiovascular risk factors (CVRFs) and subclinical atherosclerosis on brain …

[HTML][HTML] Glucose metabolism during resting state reveals abnormal brain networks organization in the Alzheimer's disease and mild cognitive impairment

G Sanabria-Diaz, E Martinez-Montes, L Melie-Garcia… - PloS one, 2013 - journals.plos.org
This paper aims to study the abnormal patterns of brain glucose metabolism co-variations in
Alzheimer disease (AD) and Mild Cognitive Impairment (MCI) patients compared to Normal …