Major histocompatibility complex genomics and human disease

J Trowsdale, JC Knight - Annual review of genomics and human …, 2013 - annualreviews.org
Over several decades, various forms of genomic analysis of the human major
histocompatibility complex (MHC) have been extremely successful in picking up many …

Aging, inflammation, immunity and periodontal disease

JL Ebersole, CL Graves, OA Gonzalez… - Periodontology …, 2016 - Wiley Online Library
The increased prevalence and severity of periodontal disease have long been associated
with aging, such that this oral condition affects the majority of the adult population over 50 …

[HTML][HTML] Extracellular vesicles derived from bone marrow mesenchymal stem cells protect against experimental colitis via attenuating colon inflammation, oxidative …

J Yang, XX Liu, H Fan, Q Tang, ZX Shou, DM Zuo… - PloS one, 2015 - journals.plos.org
The administration of bone mesenchymal stem cells (BMSCs) could reverse experimental
colitis, and the predominant mechanism in tissue repair seems to be related to their …

Inflammation‐related cytokines in oral lichen planus: an overview

R Lu, J Zhang, W Sun, G Du… - Journal of oral pathology …, 2015 - Wiley Online Library
Cytokines are powerful mediators which play a central role in both innate and adapted
immune responses. Aberrant productions of cytokines may lead to the onset of immune …

[HTML][HTML] The genetic interactions between non-alcoholic fatty liver disease and cardiovascular diseases

NWS Chew, B Chong, CH Ng, G Kong, YH Chin… - Frontiers in …, 2022 - frontiersin.org
The ongoing debate on whether non-alcoholic fatty liver disease (NAFLD) is an active
contributor or an innocent bystander in the development of cardiovascular disease (CVD) …

[HTML][HTML] A genome-wide association study of outcome from traumatic brain injury

M Kals, K Kunzmann, L Parodi, F Radmanesh… - …, 2022 - thelancet.com
Background Factors such as age, pre-injury health, and injury severity, account for less than
35% of outcome variability in traumatic brain injury (TBI). While some residual outcome …

Genetics of chronic rhinosinusitis: state of the field and directions forward

J Hsu, PC Avila, RC Kern, MG Hayes… - Journal of allergy and …, 2013 - Elsevier
The cause of chronic rhinosinusitis (CRS) remains unclear. Study of the genetic
susceptibility to CRS might be a valuable strategy to understand the pathogenesis of this …

[HTML][HTML] Anti-inflammatory intestinal activity of Arctium lappa L.(Asteraceae) in TNBS colitis model

ABA De Almeida, M Sanchez-Hidalgo… - Journal of …, 2013 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: In Brazilian traditional medicine, Arctium lappa
(Asteraceae), has been reported to relieve gastrointestinal symptoms. AIM OF THE STUDY …

Genetic variations in key inflammatory cytokines exacerbates the risk of diabetic nephropathy by influencing the gene expression

I Hameed, SR Masoodi, PA Malik, SA Mir, K Ghazanfar… - Gene, 2018 - Elsevier
Background Diabetic nephropathy is the single strongest predictor of mortality in patients
with diabetes. The development of overt nephropathy involves important inter-individual …

[HTML][HTML] Genomic aspects of NAFLD pathogenesis

A Naik, D Rozman - Genomics, 2013 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the most predominant liver disease worldwide
and hepatic manifestation of the metabolic syndrome. Its histology spectrum ranges from …