The formation, isolation and characterization of DNA adducts produced by anticancer platinum complexes
A Eastman - Pharmacology & therapeutics, 1987 - Elsevier
Since the serendipitous discovery of the biological action of platinum coordination
complexes in 1965 (Rosenberg et al., 1965), cis-diamminedichloroplatinum (cis-DDP) has …
complexes in 1965 (Rosenberg et al., 1965), cis-diamminedichloroplatinum (cis-DDP) has …
Binding of the antitumor drug cis-diamminedichloroplatinum (II)(cisplatin) to DNA
AL Pinto, SJ Lippard - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1985 - Elsevier
In 1965, an experiment designed to study the effects of electromagnetic fields on bacterial
growth revealed that the normal, rod-like shape of the bacteria could be altered when a low …
growth revealed that the normal, rod-like shape of the bacteria could be altered when a low …
Structural aspects of platinum anticancer drug interactions with DNA
SE Sherman, SJ Lippard - Chemical reviews, 1987 - ACS Publications
The classic coordination complex cis-diamminedichloroplatinum (II), 1 cis-DDP or cisplatin,
has been the subject of much recent attention because of its bene-ficial effects in the …
has been the subject of much recent attention because of its bene-ficial effects in the …
X-Ray Structure of the Major Adduct of the Anticancer Drug Cisplatin with DNA: cis-[Pt(NH3)2{d(pGpG)}]
Crystals of the adduct of the anticancer drug cis-diamminedichloroplatinum (II), cis-DDP,
with d (pGpG), its putative target on DNA in the cancer cell, have been obtained and used in …
with d (pGpG), its putative target on DNA in the cancer cell, have been obtained and used in …
[图书][B] Bioinorganic chemistry: a short course
RM Roat-Malone - 2007 - books.google.com
An updated, practical guide to bioinorganic chemistry Bioinorganic Chemistry: A Short
Course, Second Edition provides the fundamentals of inorganic chemistry and biochemistry …
Course, Second Edition provides the fundamentals of inorganic chemistry and biochemistry …
Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplex.
N Poklar, DS Pilch, SJ Lippard… - Proceedings of the …, 1996 - National Acad Sciences
cis-Diamminedichloroplatinum (II)(cisplatin) is a widely used anticancer drug that binds to
and crosslinks DNA. The major DNA adduct of the drug results from coordination of two …
and crosslinks DNA. The major DNA adduct of the drug results from coordination of two …
Sequence-dependent termination of in vitro DNA synthesis by cis-and trans-diamminedichloroplatinum (II).
AL Pinto, SJ Lippard - … of the National Academy of Sciences, 1985 - National Acad Sciences
Inhibition of DNA replication by the antitumor drug cis-diamminedichloroplatinum (II)(cis-
DDP) has been proposed to be responsible for its cytotoxicity. Treatment of primed phage …
DDP) has been proposed to be responsible for its cytotoxicity. Treatment of primed phage …
Metal antitumor compounds: the mechanism of action of platinum complexes
NP Johnson, JL Butour, G Villani, FL Wimmer… - Ruthenium and other …, 1989 - Springer
Abstract Cisplatin (cis-diamminedichloroplatinum (II)) is widely used in the treatment of
testicular and ovarian cancers. A number of biological and biochemical results indicate that …
testicular and ovarian cancers. A number of biological and biochemical results indicate that …
Chemistry and molecular biology of platinum anticancer drugs
SJ Lippard - Pure and Applied Chemistry, 1987 - degruyter.com
Chemistry and molecular biology of platinum anticancer drugs Page 1 Pure & App!. Chem.,
Vol. 59, No. 6, pp. 731—742, 1987. Printed in Great Britain. © 1987 IUPAC Chemistry and …
Vol. 59, No. 6, pp. 731—742, 1987. Printed in Great Britain. © 1987 IUPAC Chemistry and …
A molecular mechanics AMBER-type force field for modeling platinum complexes of guanine derivatives
S Yao, JP Plastaras, LG Marzilli - Inorganic Chemistry, 1994 - ACS Publications
A large number of Pt (II)/Pt (IV) complexes have been found to have anticancer activity. 1
Therecurrently exist several classes of Pt anticancer drugs, but we restrict discussionto the …
Therecurrently exist several classes of Pt anticancer drugs, but we restrict discussionto the …