An update on the management of childhood-onset systemic lupus erythematosus

VC Trindade, M Carneiro-Sampaio, E Bonfa, CA Silva - Pediatric Drugs, 2021 - Springer
Childhood-onset systemic lupus erythematosus (cSLE) is a prototype of a multisystemic,
inflammatory, heterogeneous autoimmune condition. This disease is characterized by …

Targeting DORIS remission and LLDAS in SLE: a review

AR Parra Sánchez, RF van Vollenhoven… - Rheumatology and …, 2023 - Springer
Remission is the established therapeutic goal for patients with systemic lupus
erythematosus (SLE) and is currently defined by the widely adopted Definition Of Remission …

Impact of remission and low disease activity on health-related quality of life in patients with systemic lupus erythematosus

S Emamikia, S Oon, A Gomez, J Lindblom… - …, 2022 - academic.oup.com
Objectives To investigate the impact of remission and lupus low disease activity state
(LLDAS) on health-related quality of life (HRQoL) in systemic lupus erythematosus. Methods …

Definition of low disease activity state based on the SLE-DAS: derivation and validation in a multicentre real-life cohort

H Assunção, D Jesus, M Larosa, C Henriques… - …, 2022 - academic.oup.com
Objectives To derive and validate a definition of low disease activity (LDA) for SLE based on
the SLE Disease Activity Score (SLE-DAS), in a real-life multicentre cohort of SLE patients …

Assessment of disease activity and damage in SLE: Are we there yet?

C Cruciani, M Zen, M Gatto, E Morand… - Best Practice & Research …, 2023 - Elsevier
Abstract Systemic Lupus Erythematosus is a systemic autoimmune disease characterized by
a great heterogenicity in course and clinical manifestations. Although prognosis improved in …

Potential for antigen-specific tolerizing immunotherapy in systematic lupus erythematosus

S Robinson, R Thomas - Frontiers in immunology, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) is a chronic complex systemic autoimmune disease
characterized by multiple autoantibodies and clinical manifestations, with the potential to …

EQ-5D full health state after therapy heralds reduced hazard to accrue subsequent organ damage in systemic lupus erythematosus

J Lindblom, S Zetterberg, S Emamikia, A Borg… - Frontiers in …, 2022 - frontiersin.org
Objectives To investigate whether self-reported EQ-5D full health state (FHS) after
therapeutic intervention for active systemic lupus erythematosus (SLE) is associated with a …

Efficacy of belimumab combined with rituximab in severe systemic lupus erythematosus: study protocol for the phase 3, multicenter, randomized, open-label Synbiose …

M van Schaik, EJ Arends, D Soonawala, E van Ommen… - Trials, 2022 - Springer
Background Belimumab, an anti-B-cell activating factor antibody, is approved for the
treatment of auto-antibody positive systemic lupus erythematosus with a high degree of …

Which extra-renal flare is 'difficult to treat'in systemic lupus erythematosus? A one-year longitudinal study comparing traditional and machine learning approaches

M Maffi, C Tani, G Cascarano, L Scagnellato… - …, 2024 - academic.oup.com
Objectives To describe phenotypes and outcomes of extra-renal flares in SLE, to identify
clusters of extra-renal flares based on baseline features, and to develop a machine learning …

Long-term clinical outcome in systemic lupus erythematosus patients followed for more than 20 years: the Milan systemic lupus erythematosus consortium (SMiLE) …

M Gerosa, L Beretta, GA Ramirez, E Bozzolo… - Journal of Clinical …, 2022 - mdpi.com
Tackling active disease to prevent damage accrual constitutes a major goal in the
management of patients with systemic lupus erythematosus (SLE). Patients with early onset …