Self-assembly has emerged as an extensively used method for constructing biomaterials
with sizes ranging from nanometers to micrometers. Peptides have been extensively …

Abnormal enzymatic activities are directly related to the development of cancers. Identifying
the location and expression levels of these enzymes in live cancer cells have considerable …

Enzymatic reactions and noncovalent (ie, supramolecular) interactions are two fundamental
nongenetic attributes of life. Enzymatic noncovalent synthesis (ENS) refers to a process …

Lysosomes remain powerful organelles and important targets for cancer therapy because
cancer cell proliferation is greatly dependent on effective lysosomal function. Recent studies …

Conspectus Higher-order or supramolecular protein assemblies, usually regulated by
enzymatic reactions, are ubiquitous and essential for cellular functions. This evolutionary …

Incorporation of non‐equilibrium actions in the sequence of self‐assembly processes would
be an effective means to establish bio‐like high functionality hierarchical assemblies. As a …

Human epidermal growth factor receptor 2 (HER2) is overexpressed in> 20% of breast
cancers. Dimerization of HER2 receptors leads to the activation of downstream signals …

Cell spheroids bridge the discontinuity between in vitro systems and in vivo animal models.
However, inducing cell spheroids by nanomaterials remains an inefficient and poorly …

Although nanomedicines can passively target tumor through the enhanced permeability and
retention (EPR) effect, their distribution and retention are limited by complex tumor …

The self-assembly and structural and functional properties of peptide conjugates containing
bulky terminal aromatic substituents are reviewed with a particular focus on bioactivity …