Electrochemical transformations catalyzed by cytochrome P450s and peroxidases
Cytochrome P450s (Cyt P450s) and peroxidases are enzymes featuring iron heme cofactors
that have wide applicability as biocatalysts in chemical syntheses. Cyt P450s are a family of …
that have wide applicability as biocatalysts in chemical syntheses. Cyt P450s are a family of …
Efficient heterologous expression of cytochrome P450 enzymes in microorganisms for the biosynthesis of natural products
Natural products, a chemically and structurally diverse class of molecules, possess a wide
spectrum of biological activities, have been used therapeutically for millennia, and have …
spectrum of biological activities, have been used therapeutically for millennia, and have …
Combining a Genetically Engineered Oxidase with Hydrogen‐Bonded Organic Frameworks (HOFs) for Highly Efficient Biocomposites
Enzymes incorporated into hydrogen‐bonded organic frameworks (HOFs) via bottom‐up
synthesis are promising biocomposites for applications in catalysis and sensing. Here, we …
synthesis are promising biocomposites for applications in catalysis and sensing. Here, we …
[HTML][HTML] Biocatalytic process intensification via efficient biocatalyst immobilization, miniaturization, and process integration
P Žnidaršič-Plazl - Current Opinion in Green and Sustainable Chemistry, 2021 - Elsevier
Despite their sustainability, the potential of biocatalytic processes in industrial production is
far from being realized. The main challenges in this field are the development of highly …
far from being realized. The main challenges in this field are the development of highly …
Whole-cell biocatalysis using cytochrome P450 monooxygenases for biotransformation of sustainable bioresources (fatty acids, fatty alkanes, and aromatic amino …
HA Park, G Park, W Jeon, JO Ahn, YH Yang… - Biotechnology …, 2020 - Elsevier
Cytochrome P450s (CYPs) are heme-thiolated enzymes that catalyze the oxidation of C
single bond H bonds in a regio and stereoselective manner. Activation of the non-activated …
single bond H bonds in a regio and stereoselective manner. Activation of the non-activated …
An overview of cytochrome P450 immobilization strategies for drug metabolism studies, biosensing, and biocatalytic applications: challenges and opportunities
Cytochrome P450s (P450s or CYPs) are a large superfamily of ubiquitous heme proteins.
Consistent with their natural roles in oxidative metabolism of a broad range of substrates …
Consistent with their natural roles in oxidative metabolism of a broad range of substrates …
Choose Your Own Adventure: A Comprehensive Database of Reactions Catalyzed by Cytochrome P450 BM3 Variants
DJ Fansher, JN Besna, A Fendri, JN Pelletier - ACS catalysis, 2024 - ACS Publications
Cytochrome P450 BM3 monooxygenase is the topic of extensive research as many
researchers have evolved this enzyme to generate a variety of products. However, the …
researchers have evolved this enzyme to generate a variety of products. However, the …
MicroGelzymes: pH-independent immobilization of cytochrome P450 BM3 in microgels
M Nöth, L Hussmann, T Belthle, I El-Awaad… - …, 2020 - ACS Publications
Microgels are an emerging class of “ideal” enzyme carriers because of their chemical and
process stability, biocompatibility, and high enzyme loading capability. In this work, we …
process stability, biocompatibility, and high enzyme loading capability. In this work, we …
On the relationship between structure and catalytic effectiveness in solid surface-immobilized enzymes: Advances in methodology and the quest for a single-molecule …
JM Bolivar, B Nidetzky - Biochimica et Biophysica Acta (BBA)-Proteins and …, 2020 - Elsevier
The integration of enzymes with solid materials is important in many biotechnological
applications, including the use of immobilized enzymes for biocatalytic synthesis. The …
applications, including the use of immobilized enzymes for biocatalytic synthesis. The …
Co‐immobilization and colocalization of multi‐enzyme systems for the cell‐free biosynthesis of aminoalcohols
S Velasco‐Lozano, J Santiago‐Arcos… - …, 2020 - Wiley Online Library
The manufacturing of aminoalcohols is an appealing transformation for industrial
biocatalysis due to their high value as building blocks in synthetic chemistry. By co …
biocatalysis due to their high value as building blocks in synthetic chemistry. By co …