T cell receptor beta germline variability is revealed by inference from repertoire data
Background T and B cell receptor (TCR, BCR) repertoires constitute the foundation of
adaptive immunity. Adaptive immune receptor repertoire sequencing (AIRR-seq) is a …
adaptive immunity. Adaptive immune receptor repertoire sequencing (AIRR-seq) is a …
Targeted long-read sequencing facilitates phased diploid assembly and genotyping of the human T cell receptor alpha, delta, and beta loci
OL Rodriguez, CA Silver, K Shields, ML Smith… - Cell Genomics, 2022 - cell.com
T cell receptors (TCRs) recognize peptide fragments presented by the major
histocompatibility complex (MHC) and are critical to T cell-mediated immunity. Recent data …
histocompatibility complex (MHC) and are critical to T cell-mediated immunity. Recent data …
pmTR database: population matched (pm) germline allelic variants of T-cell receptor (TR) loci
The IMGT database profiles the TR germline alleles for all four TR loci (TRA, TRB, TRG and
TRD), however, it does not comprise of the information regarding population specificity and …
TRD), however, it does not comprise of the information regarding population specificity and …