Sand flies: Basic information on the vectors of leishmaniasis and their interactions with Leishmania parasites

P Cecílio, A Cordeiro-da-Silva, F Oliveira - Communications biology, 2022 - nature.com
Blood-sucking arthropods transmit a variety of human pathogens acting as disseminators of
the so-called vector-borne diseases. Leishmaniasis is a spectrum of diseases caused by …

Euglenozoa: taxonomy, diversity and ecology, symbioses and viruses

AY Kostygov, A Karnkowska, J Votýpka… - Open …, 2021 - royalsocietypublishing.org
Euglenozoa is a species-rich group of protists, which have extremely diverse lifestyles and a
range of features that distinguish them from other eukaryotes. They are composed of free …

[HTML][HTML] Host immune response against leishmaniasis and parasite persistence strategies: A review and assessment of recent research

EK Elmahallawy, AAM Alkhaldi, AA Saleh - Biomedicine & …, 2021 - Elsevier
Leishmaniasis, a neglected parasitic disease caused by a unicellular protozoan of the
genus Leishmania, is transmitted through the bite of a female sandfly. The disease remains …

Genetic dissection of a Leishmania flagellar proteome demonstrates requirement for directional motility in sand fly infections

T Beneke, F Demay, E Hookway, N Ashman… - PLoS …, 2019 - journals.plos.org
The protozoan parasite Leishmania possesses a single flagellum, which is remodelled
during the parasite's life cycle from a long motile flagellum in promastigote forms in the sand …

Leishmania Immunity: Advancing Immunotherapy and Vaccine Development

NM Ikeogu, GN Akaluka, CA Edechi, ES Salako… - Microorganisms, 2020 - mdpi.com
Parasitic diseases still constitute a major global health problem affecting billions of people
around the world. These diseases are capable of becoming chronic and result in high …

Host–pathogen interaction in leishmaniasis: immune response and vaccination strategies

H Yasmin, A Adhikary, MN Al-Ahdal, S Roy, U Kishore - Immuno, 2022 - mdpi.com
Leishmaniasis is a zoonotic and vector-borne infectious disease that is caused by the genus
Leishmania belonging to the trypanosomatid family. The protozoan parasite has a digenetic …

Formation and three-dimensional architecture of Leishmania adhesion in the sand fly vector

R Yanase, F Moreira-Leite, E Rea, L Wilburn… - elife, 2023 - elifesciences.org
Attachment to a substrate to maintain position in a specific ecological niche is a common
strategy across biology, especially for eukaryotic parasites. During development in the sand …

Activity of Anti-Microbial Peptides (AMPs) against Leishmania and Other Parasites: An Overview

R El-Dirany, H Shahrour, Z Dirany, F Abdel-Sater… - Biomolecules, 2021 - mdpi.com
Anti-microbial peptides (AMPs), small biologically active molecules, produced by different
organisms through their innate immune system, have become a considerable subject of …

Discovery of essential kinetoplastid-insect adhesion proteins and their function in Leishmania-sand fly interactions

R Yanase, K Pruzinova, BO Owino, E Rea… - Nature …, 2024 - nature.com
Leishmania species, members of the kinetoplastid parasites, cause leishmaniasis, a
neglected tropical disease, in millions of people worldwide. Leishmania has a complex life …

Identification of potential inhibitor against Leishmania donovani mitochondrial DNA primase through in-silico and in vitro drug repurposing approaches

M Nath, D Bhowmik, S Saha, R Nandi, D Kumar - Scientific Reports, 2024 - nature.com
Leishmania donovani is the causal organism of leishmaniasis with critical health
implications affecting about 12 million people around the globe. Due to less efficacy …