Prostatic fibrosis, lower urinary tract symptoms, and BPH
JA Rodriguez-Nieves, JA Macoska - Nature Reviews Urology, 2013 - nature.com
Lower urinary tract symptoms (LUTS)—constituting a spectrum disorder that encompasses
weak stream, nocturia, and sensations of incomplete emptying and intermittent or hesitant …
weak stream, nocturia, and sensations of incomplete emptying and intermittent or hesitant …
Benign prostatic hyperplasia and lower urinary tract symptoms: what is the role and significance of inflammation?
GL Lloyd, JM Marks, WA Ricke - Current urology reports, 2019 - Springer
Abstract Purpose of Review The purpose of this review is to summarize the role and
significance of inflammation as a putative additional factor contributing to lower urinary tract …
significance of inflammation as a putative additional factor contributing to lower urinary tract …
Estrogen and G protein-coupled estrogen receptor accelerate the progression of benign prostatic hyperplasia by inducing prostatic fibrosis
Y Yang, J Sheng, S Hu, Y Cui, J Xiao, W Yu… - Cell death & …, 2022 - nature.com
Benign prostatic hyperplasia (BPH) is the most common and progressive urological disease
in elderly men worldwide. Epidemiological studies have suggested that the speed of …
in elderly men worldwide. Epidemiological studies have suggested that the speed of …
Fluorescence of picrosirius red multiplexed with immunohistochemistry for the quantitative assessment of collagen in tissue sections
KA Wegner, A Keikhosravi… - … of Histochemistry & …, 2017 - journals.sagepub.com
The low cost and simplicity of picrosirius red (PSR) staining have driven its popularity for
collagen detection in tissue sections. We extended the versatility of this method by using …
collagen detection in tissue sections. We extended the versatility of this method by using …
Causal contributors to tissue stiffness and clinical relevance in urology
L Martinez-Vidal, V Murdica, C Venegoni… - Communications …, 2021 - nature.com
Mechanomedicine is an emerging field focused on characterizing mechanical changes in
cells and tissues coupled with a specific disease. Understanding the mechanical cues that …
cells and tissues coupled with a specific disease. Understanding the mechanical cues that …
Oxidative stress promotes benign prostatic hyperplasia
P Vital, P Castro, M Ittmann - The Prostate, 2016 - Wiley Online Library
BACKGROUND Benign prostatic hyperplasia (BPH) is characterized by increased tissue
mass in the transition zone of the prostate, which leads to obstruction of urine outflow and …
mass in the transition zone of the prostate, which leads to obstruction of urine outflow and …
The role of prostate inflammation and fibrosis in lower urinary tract symptoms
WA Bushman, TJ Jerde - American Journal of Physiology …, 2016 - journals.physiology.org
Lower urinary tract symptoms (LUTS) in aging men are extremely common. They have
historically been attributed to benign prostatic hyperplasia (BPH), enlargement of the …
historically been attributed to benign prostatic hyperplasia (BPH), enlargement of the …
Characterization of fibrillar collagens and extracellular matrix of glandular benign prostatic hyperplasia nodules
Objective Recent studies have associated lower urinary tract symptoms (LUTS) in men with
prostatic fibrosis, but a definitive link between collagen deposition and LUTS has yet to be …
prostatic fibrosis, but a definitive link between collagen deposition and LUTS has yet to be …
Targeting phenotypic heterogeneity in benign prostatic hyperplasia
DW Strand, DN Costa, F Francis, WA Ricke… - Differentiation, 2017 - Elsevier
Benign prostatic hyperplasia and associated lower urinary tract symptoms remain difficult to
treat medically, resulting in hundreds of thousands of surgeries performed annually in …
treat medically, resulting in hundreds of thousands of surgeries performed annually in …
Periurethral fibrosis secondary to prostatic inflammation causing lower urinary tract symptoms: a prospective cohort study
F Cantiello, A Cicione, A Salonia, R Autorino, L Tucci… - Urology, 2013 - Elsevier
OBJECTIVE: To investigate the role periurethral fibrosis secondary to chronic prostatic
inflammation as a potential contributing factor to the etiology of lower urinary tract symptoms …
inflammation as a potential contributing factor to the etiology of lower urinary tract symptoms …