Impact of 3D hierarchical nanostructures on the antibacterial efficacy of a bacteria-triggered self-defensive antibiotic coating

F Hizal, I Zhuk, S Sukhishvili, HJ Busscher… - … applied materials & …, 2015 - ACS Publications
Titanium is often applied in implant surgery, but frequently implicated in infections
associated with bacterial adhesion and growth on the implant surface. Here, we show that …

An additive to PMMA bone cement enables postimplantation drug refilling, broadens range of compatible antibiotics, and prolongs antimicrobial therapy

EL Cyphert, GD Learn, SK Hurley, C Lu… - Advanced …, 2018 - Wiley Online Library
Abstract Poly (methyl methacrylate)(PMMA) bone cement is used in several biomedical
applications including as antibiotic‐filled beads, temporary skeletal spacers, and cement for …

Diatoms decorated with gold nanoparticles by In-situ and Ex-situ methods for in vitro gentamicin release

S Briceño, EA Chavez-Chico, G González - Materials Science and …, 2021 - Elsevier
The use of natural diatoms is currently a topic of interest for therapeutic applications due to
its facilities, low cost, and biocompatibility. Here, we report the chemical modification of …

Inclusion of hydroxytyrosol in ethyl cellulose microparticles: In vitro release studies under digestion conditions

F Paulo, L Santos - Food hydrocolloids, 2018 - Elsevier
Hydroxytyrosol, existing at high concentrations in olive oil, presents remarkable health
benefits mainly due to its antioxidant properties. Nevertheless, the inclusion of …

Extraction and encapsulation of bioactive compounds from olive mill pomace: Influence of loading content on the physicochemical and structural properties of …

F Paulo, L Tavares, L Santos - Journal of Food Measurement and …, 2022 - Springer
Extraction and encapsulation techniques can be combined to reduce the environmental
impact of olive mill pomace (OMP) wastes due to their high content of phenolic compounds …

[HTML][HTML] Optimization and formulation of fucoxanthin-loaded microsphere (F-LM) using response surface methodology (RSM) and analysis of its fucoxanthin release …

I Jaswir, D Noviendri, M Taher, F Mohamed… - Molecules, 2019 - mdpi.com
Fucoxanthin has interesting anticancer activity, but is insoluble in water, hindering its use as
a drug. Microencapsulation is used as a technique for improving drug delivery. This study …

Gentamicin-loaded thermosetting hydrogel and moldable composite scaffold: formulation study and biologic evaluation

R Dorati, A De Trizio, I Genta, A Merelli… - Journal of …, 2017 - Elsevier
The aim was to design biodegradable drug delivery systems for gentamicin local delivery,
meanwhile acting as scaffold for bone regeneration. Gentamicin-loaded thermosetting …

Co-encapsulation of Nigella sativa oil and plasmid DNA for enhanced gene therapy of Alzheimer's disease

AA Doolaanea, NI Mansor, NH Mohd Nor… - Journal of …, 2016 - Taylor & Francis
Alzheimer disease involves genetic and non-genetic factors and hence it is rational to be
treated with genetic and non-genetic therapeutic agents. Nigella sativa has multiple …

An experimental design approach to the preparation of pegylated polylactide-co-glicolide gentamicin loaded microparticles for local antibiotic delivery

R Dorati, A DeTrizio, I Genta, P Grisoli, A Merelli… - Materials Science and …, 2016 - Elsevier
The present paper takes into account the DOE application to the preparation process of
biodegradable microspheres for osteomyelitis local therapy. With this goal gentamicin …

Spectrophotometric determination of gentamicin loaded PLGA microparticles and method validation via ninhydrin-gentamicin complex as a rapid quantification …

AFH Ismail, F Mohamed, LMM Rosli… - Journal of Applied …, 2016 - japsonline.com
The purpose of this study was to provide a quantification method with rapid, sensitive,
reproducible and cost effective for gentamicin in the form of ninhydrin-gentamicin complex …