Immunogenic cell death activates the tumor immune microenvironment to boost the immunotherapy efficiency

Z Li, X Lai, S Fu, L Ren, H Cai, H Zhang, Z Gu… - Advanced …, 2022 - Wiley Online Library
Tumor immunotherapy is only effective in a fraction of patients due to a low response rate
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …

Minimally invasive nanomedicine: nanotechnology in photo-/ultrasound-/radiation-/magnetism-mediated therapy and imaging

J Ouyang, A Xie, J Zhou, R Liu, L Wang, H Liu… - Chemical Society …, 2022 - pubs.rsc.org
Traditional treatments such as chemotherapy and surgery usually cause severe side effects
and excruciating pain. The emergence of nanomedicines and minimally invasive therapies …

Pyroptosis‐Mediated Synergistic Photodynamic and Photothermal Immunotherapy Enabled by a Tumor‐Membrane‐Targeted Photosensitive Dimer

Y Tang, HK Bisoyi, XM Chen, Z Liu, X Chen… - Advanced …, 2023 - Wiley Online Library
Overcoming the resistance to apoptosis and immunosuppression of tumor cells is a
significant challenge in augmenting the effect of cancer immunotherapy. Pyroptosis, a lytic …

Tumor‐microenvironment‐responsive nanomedicine for enhanced cancer immunotherapy

S Peng, F Xiao, M Chen, H Gao - Advanced Science, 2022 - Wiley Online Library
The past decades have witnessed great progress in cancer immunotherapy, which has
profoundly revolutionized oncology, whereas low patient response rates and potential …

Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer

Y Jiang, J Huang, C Xu, K Pu - Nature communications, 2021 - nature.com
Nanomedicine in combination with immunotherapy offers opportunities to treat cancer in a
safe and effective manner; however, remote control of immune response with spatiotemporal …

Vaccine-like nanomedicine for cancer immunotherapy

Y Yi, M Yu, W Li, D Zhu, L Mei, M Ou - Journal of Controlled Release, 2023 - Elsevier
The successful clinical application of immune checkpoint blockade (ICB) and chimeric
antigen receptor T cells (CAR-T) therapeutics has attracted extensive attention to …

Stabilizing Perovskite Precursor by Synergy of Functional Groups for NiOx‐Based Inverted Solar Cells with 23.5 % Efficiency

M Li, H Li, Q Zhuang, D He, B Liu, C Chen… - Angewandte …, 2022 - Wiley Online Library
Perovskite solar cells suffer from poor reproducibility due to the degradation of perovskite
precursor solution. Herein, we report an effective precursor stabilization strategy via …

A nitric-oxide driven chemotactic nanomotor for enhanced immunotherapy of glioblastoma

H Chen, T Li, Z Liu, S Tang, J Tong, Y Tao… - Nature …, 2023 - nature.com
The major challenges of immunotherapy for glioblastoma are that drugs cannot target tumor
sites accurately and properly activate complex immune responses. Herein, we design and …

Biomineralized MnO2 Nanoplatforms Mediated Delivery of Immune Checkpoint Inhibitors with STING Pathway Activation to Potentiate Cancer Radio-Immunotherapy

Z Deng, M Xi, C Zhang, X Wu, Q Li, C Wang, H Fang… - ACS …, 2023 - ACS Publications
Radiotherapy (RT), as one of the main methods in the clinical treatment of various malignant
tumors, would induce systemic immunotherapeutic effects by triggering immunogenic cell …

Stimuli‐responsive nanoparticles for controlled drug delivery in synergistic cancer immunotherapy

J Zhang, Y Lin, Z Lin, Q Wei, J Qian, R Ruan… - Advanced …, 2022 - Wiley Online Library
Cancer immunotherapy has achieved promising clinical progress over the recent years for
its potential to treat metastatic tumors and inhibit their recurrences effectively. However, low …