Strategies to develop polymeric microneedles for controlled drug release

BZ Chen, YT He, ZQ Zhao, YH Feng, L Liang… - Advanced Drug Delivery …, 2023 - Elsevier
The remarkable appeal of microneedle controlled-release systems has captivated both the
academic community and pharmaceutical industry due to their great potential for achieving …

Recent advances in oral and transdermal protein delivery systems

Y Yang, R Zhou, Y Wang, Y Zhang, J Yu… - Angewandte …, 2023 - Wiley Online Library
Protein and peptide drugs are predominantly administered by injection to achieve high
bioavailability, but this greatly compromises patient compliance. Oral and transdermal drug …

Porcupine-inspired microneedles coupled with an adhesive back patching as dressing for accelerating diabetic wound healing

T Liu, Y Sun, G Jiang, W Zhang, R Wang, L Nie… - Acta Biomaterialia, 2023 - Elsevier
Diabetes chronic wound is a severe and frequently occurring medical issue in patients with
diabetes that often leads to more serious complications. Microneedles (MNs) can be used …

Hyaluronic acid-based CuS nanoenzyme biodegradable microneedles for treating deep cutaneous fungal infection without drug resistance

B Wang, W Zhang, Q Pan, J Tao, S Li, T Jiang… - Nano …, 2023 - ACS Publications
Deep cutaneous fungal infection (DCFI) is difficult to be treated by the traditional topical
application due to low drug transdermal efficiency, poor fungicidal effect, and easy to …

[HTML][HTML] Microneedle-enabled therapeutics delivery and biosensing in clinical trials

J Zhang, H Li, L Albakr, Y Zhang, A Lu, W Chen… - Journal of Controlled …, 2023 - Elsevier
Microneedles (MNs) are micron-sized protrusions attached to a range of devices that are
used in therapeutic delivery and diagnosis. Because MNs can be self-applied, are painless …

Microneedles as a momentous platform for psoriasis therapy and diagnosis: A state-of-the-art review

BHJ Gowda, MG Ahmed, U Hani, P Kesharwani… - International Journal of …, 2023 - Elsevier
Psoriasis is a chronic, autoimmune, and non-communicable skin disease with a worldwide
prevalence rate of 2–3%, creating an economic burden on global health. Some significant …

Microneedle-mediated transdermal delivery of biopharmaceuticals

HX Nguyen, CN Nguyen - Pharmaceutics, 2023 - mdpi.com
Transdermal delivery provides numerous benefits over conventional routes of
administration. However, this strategy is generally limited to a few molecules with specific …

Microneedle-based glucose monitoring: a review from sampling methods to wearable biosensors

Y Wang, Y Wu, Y Lei - Biomaterials Science, 2023 - pubs.rsc.org
Blood glucose (BG) monitoring is critical for diabetes management. In recent years,
microneedle (MN)-based technology has attracted emerging attention in glucose sensing …

[HTML][HTML] Assessing the risk of a clinically significant infection from a Microneedle Array Patch (MAP) product

M Dul, M Alali, M Ameri, MD Burke, CM Craig… - Journal of Controlled …, 2023 - Elsevier
Abstract Microneedle Array Patches (MAPs) are an emerging dosage form that creates
transient micron-sized disruptions in the outermost physical skin barrier, the stratum …

Microneedle‐assisted transdermal delivery of nanoparticles: Recent insights and prospects

AJ Guillot, M Martínez‐Navarrete… - Wiley …, 2023 - Wiley Online Library
Transdermal delivery of drugs offers an interesting alternative for the administration of
molecules that present certain troubles when delivered by the oral route. It can produce …