Optimized CRISPR/cas9 systems and methods for gene editing in stem cells
JL Gori - US Patent 11,390,884, 2022 - Google Patents
QFJCIRLUMZQUOT-HPLJOQBZSA-N Sirolimus Chemical compound C1C [C@@ H](O)[C@
H](OC) C [C@@ H] 1C [C@@ H](C)[C@ H] 1OC (= O)[C@@ H] 2CCCCN2C (= O) C …
H](OC) C [C@@ H] 1C [C@@ H](C)[C@ H] 1OC (= O)[C@@ H] 2CCCCN2C (= O) C …
Systems and methods for targeted integration and genome editing and detection thereof using integrated priming sites
C Cotta-Ramusino, CM Margulies - US Patent 11,866,726, 2024 - Google Patents
US11866726B2 - Systems and methods for targeted integration and genome editing and
detection thereof using integrated priming sites - Google Patents US11866726B2 - Systems …
detection thereof using integrated priming sites - Google Patents US11866726B2 - Systems …
Methods for targeted insertion of DNA in genes
NJ Baltes - US Patent 11,254,930, 2022 - Google Patents
Monogenic disorders are caused by one or more mutations in a single gene, examples of
which include sickle cell disease (hemoglobin-beta gene), cystic fibrosis (cystic fibrosis …
which include sickle cell disease (hemoglobin-beta gene), cystic fibrosis (cystic fibrosis …
Methods for targeted insertion of dna in genes
NJ Baltes - US Patent 11,091,756, 2021 - Google Patents
US11091756B2 - Methods for targeted insertion of dna in genes - Google Patents US11091756B2
- Methods for targeted insertion of dna in genes - Google Patents Methods for targeted insertion …
- Methods for targeted insertion of dna in genes - Google Patents Methods for targeted insertion …
Gene editing for autoimmune disorders
M Rabinowitz - US Patent App. 17/054,619, 2021 - Google Patents
Provided are methods treating a subject having an autoim mune disorder comprising, for
instance, decreasing, in one or more cells in the subject, the amount of one or more genetic …
instance, decreasing, in one or more cells in the subject, the amount of one or more genetic …
Methods for targeted insertion of DNA in genes
NJ Baltes - US Patent 12,054,706, 2024 - Google Patents
US12054706B2 - Methods for targeted insertion of DNA in genes - Google Patents
US12054706B2 - Methods for targeted insertion of DNA in genes - Google Patents Methods for …
US12054706B2 - Methods for targeted insertion of DNA in genes - Google Patents Methods for …
Methods for targeted insertion of DNA in genes
NJ Baltes - US Patent 11,993,770, 2024 - Google Patents
US11993770B2 - Methods for targeted insertion of DNA in genes - Google Patents
US11993770B2 - Methods for targeted insertion of DNA in genes - Google Patents Methods for …
US11993770B2 - Methods for targeted insertion of DNA in genes - Google Patents Methods for …
Methods for targeted insertion of DNA in genes
NJ Baltes - US Patent 11,365,407, 2022 - Google Patents
US11365407B2 - Methods for targeted insertion of DNA in genes - Google Patents
US11365407B2 - Methods for targeted insertion of DNA in genes - Google Patents Methods for …
US11365407B2 - Methods for targeted insertion of DNA in genes - Google Patents Methods for …
Methods of treating rheumatoid arthritis using RNA-guided genome editing of HLA gene
B Freed, K Anderson, C Roark, J Matsuda - US Patent 11,932,867, 2024 - Google Patents
Methods of preventing or treating rheumatoid arthritis (RA) in a subject by introducing the
DRB1* 04: 01 “" mutation that is resistant to RA. The resistant allele is introduced into the …
DRB1* 04: 01 “" mutation that is resistant to RA. The resistant allele is introduced into the …
Target-specific CRISPR mutant
YH Kim, MH Jung, LEE Joonsun, E Shin… - US Patent …, 2022 - Google Patents
The present invention relates to an artificially engineered CRISPR/Cas9 system. More
particularly, the present invention relates to an artificially engineered CRISPR enzyme …
particularly, the present invention relates to an artificially engineered CRISPR enzyme …