In pharmaceutical research and development, various new chemical entities (NCE) are
found to be poorly water-soluble. Therefore, solubility enhancement, a key factor for higher …

Hydroxypropyl methylcellulose (HPMC) is an important polymeric excipient. Its versatility in
terms of molecular weights and viscosity grades is the basis for its wide and successful …

Cellulose probably is the most abundant organic compound in the world which mostly
produced by plants. It is the most structural component in herbal cells and tissues. Cellulose …

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Introduction: Oral drug delivery is the most favored route of drug administration. However …

The introduction of the biopharmaceutics drug classification system (Biopharmaceutics
Classification System (BCS)), in 1995, provided a simple way to describe the …

Simultaneous micronization and surface modification of drug particles is considered in order
to mitigate disadvantages of micronization, eg, agglomeration, poor flowability, marginal …

In the present work, complexes of simvastatin (SIM) with polysaccharide arabinogalactan
(AG) or disodium salt of glycyrrhizin acid (Na 2 GA) have been prepared using …

Introduction: Today, the properties of many new chemical entities have shifted towards
higher molecular weights and this in turn increases the lipophilicity hence decreasing …

The oral solid dosage forms are extremely relevant to drug therapy and responsible for
much of the pharmaceutical industry turnover worldwide. However, the development of …

Context: The liquisolid technology is a promising technique for the release enhancement of
poorly soluble drugs. With this approach, liquids such as solutions or suspensions of poorly …