Protein-based biological materials: Molecular design and artificial production

A Miserez, J Yu, P Mohammadi - Chemical Reviews, 2023 - ACS Publications
Polymeric materials produced from fossil fuels have been intimately linked to the
development of industrial activities in the 20th century and, consequently, to the …

Half a century of amyloids: past, present and future

PC Ke, R Zhou, LC Serpell, R Riek… - Chemical Society …, 2020 - pubs.rsc.org
Amyloid diseases are global epidemics with profound health, social and economic
implications and yet remain without a cure. This dire situation calls for research into the …

Functional amyloids

D Otzen, R Riek - Cold Spring Harbor perspectives in …, 2019 - cshperspectives.cshlp.org
When protein/peptides aggregate, they usually form the amyloid state consisting of cross β-
sheet structure built by repetitively stacked β-strands forming long fibrils. Amyloids are …

The role of microbial amyloid in neurodegeneration

RP Friedland, MR Chapman - PLoS pathogens, 2017 - journals.plos.org
It has become apparent that the intestinal microbiota orchestrates important aspects of our
metabolism, immunity, and development. Recent work has demonstrated that the microbiota …

Innate immunity in Alzheimer's disease

MT Heneka, DT Golenbock, E Latz - Nature immunology, 2015 - nature.com
Alzheimer's disease (AD) is the world's most common dementing illness, affecting over 150
million patients. Classically AD has been viewed as a neurodegenerative disease of the …

Giving structure to the biofilm matrix: an overview of individual strategies and emerging common themes

L Hobley, C Harkins, CE MacPhee… - FEMS microbiology …, 2015 - academic.oup.com
Biofilms are communities of microbial cells that underpin diverse processes including
sewage bioremediation, plant growth promotion, chronic infections and industrial biofouling …

Structure and aggregation mechanisms in amyloids

ZL Almeida, RMM Brito - Molecules, 2020 - mdpi.com
The aggregation of a polypeptide chain into amyloid fibrils and their accumulation and
deposition into insoluble plaques and intracellular inclusions is the hallmark of several …

Nanomechanics of functional and pathological amyloid materials

TPJ Knowles, MJ Buehler - Nature nanotechnology, 2011 - nature.com
Amyloid or amyloid-like fibrils represent a general class of nanomaterials that can be formed
from many different peptides and proteins. Although these structures have an important role …

Immune activation in brain aging and neurodegeneration: too much or too little?

KM Lucin, T Wyss-Coray - Neuron, 2009 - cell.com
Until recently, the brain was studied almost exclusively by neuroscientists and the immune
system by immunologists, fuelling the notion that these systems represented two isolated …

[HTML][HTML] Molecular characterisation of csgA gene among ESBL strains of A. baumannii and targeting with essential oil compounds from Azadirachta indica

AI Jaisankar, ASS Girija, S Gunasekaran… - Journal of King Saud …, 2020 - Elsevier
Objectives A. baumannii is considered as a “red alert” nosocomial human pathogen and
exhibits an extensive antibiotic resistance spectrum. The biofilm formation mediated by the …