Publisher Summary This chapter discusses the key adhesion molecules involved in
leukocyte trafficking to sites of inflammation, focuses on mechanisms to regulate adhesion …

Publisher Summary This chapter explores the field of investigation that has combined in an
effective way the power of new technologies including recombinant DNA technology and …

L-selectin, a cell adhesion molecule expressed by leukocytes, mediates the attachment of
lymphocytes to high endothelial venules (HEV) of peripheral lymph nodes and mediates the …

Leukostasis and tissue infiltration by leukemic cells are poorly understood life-threatening
complications of acute leukemia. This study has tested the hypothesis that adhesion …

L-selectin expressed by granulocytes, lymphocytes, and monocytes is responsible for initial
leukocyte attachment to inflamed endothelium and high endothelial venules of peripheral …

Leukocyte interactions with vascular endothelium at sites of inflammation can be
dynamically regulated by activation-dependent adhesion molecules. Current models …

Specific arrest of neutrophils in venules is central to their rapid accumulation during local
inflammatory responses. Initial neutrophil rolling on endothelium is mediated by leukocyte L …

Neutrophil accumulation is a hallmark of immune complex-mediated inflammatory disorders.
Current models of neutrophil recruitment envision the capture of circulating neutrophils by …

Selectins play a critical role in initiating leukocyte binding to vascular endothelium. In
addition, in vitro experiments have shown that neutrophils use L-selectin to roll on adherent …

A proportion of T cells recirculate in a tissue‐selective manner. Recent studies which
showed that the skin‐tropic subset of T cells was of memory/activated type, led us to …