Cellular senescence in type 2 diabetes: a therapeutic opportunity

AK Palmer, T Tchkonia, NK LeBrasseur, EN Chini… - Diabetes, 2015 - Am Diabetes Assoc
Cellular senescence is a fundamental aging mechanism that has been implicated in many
age-related diseases and is a significant cause of tissue dysfunction. Accumulation of …

The impact of childhood obesity on inflammation, innate immune cell frequency, and metabolic microRNA expression

E Carolan, AE Hogan, M Corrigan… - The Journal of …, 2014 - academic.oup.com
Background: Obesity is characterized by chronic inflammation, immune dysregulation, and
alteration of gene expression, associated with type 2 diabetes mellitus and cardiovascular …

Analysis of inflammatory mediators in type 2 diabetes patients

A Al-Shukaili, S Al-Ghafri, S Al-Marhoobi… - International journal …, 2013 - Wiley Online Library
The main aim of this study is to assess the inflammatory markers in type 2 diabetes mellitus
(T2DM) by measuring some cytokines concentrations and lymphocytes subset and correlate …

Evidence in obese children: contribution of hyperlipidemia, obesity-inflammation, and insulin sensitivity

CJ Chang, DY Jian, MW Lin, JZ Zhao, LT Ho, CC Juan - PloS one, 2015 - journals.plos.org
Background Evidence shows a high incidence of insulin resistance, inflammation and
dyslipidemia in adult obesity. The aim of this study was to assess the relevance of …

Comparison of IPAQ-SF and two other physical activity questionnaires with accelerometer in adolescent boys

T Rääsk, J Mäestu, E Lätt, J Jürimäe, T Jürimäe… - PloS one, 2017 - journals.plos.org
Self-report measures of physical activity (PA) are easy to use and popular but their reliability
is often questioned. Therefore, the general aim of the present study was to investigate the …

Pro-inflammatory cytokine associated with somatic and pain symptoms in depression

YM Bai, WF Chiou, TP Su, CT Li, MH Chen - Journal of affective disorders, 2014 - Elsevier
Background More than two-thirds of depressed patients complain of somatic and pain
symptoms, which are frequently regarded as a psychological reaction. Although there is a …

Puberty dysregulation and increased risk of disease in adult life: possible modes of action

A Mantovani, A Fucic - Reproductive Toxicology, 2014 - Elsevier
Puberty is the developmental window when the final maturation of body systems is
orchestrated by hormones; lifelong sex-related differences and capacity to interact with the …

Unraveling and targeting myocardial regeneration deficit in diabetes

C Molinaro, L Salerno, F Marino, M Scalise, N Salerno… - Antioxidants, 2022 - mdpi.com
Cardiomyopathy is a common complication in diabetic patients. Ventricular dysfunction
without coronary atherosclerosis and hypertension is driven by hyperglycemia …

Effects of probiotic supplementation on exercise and the underlying mechanisms

L Zhang, R Zhang, L Li - Foods, 2023 - mdpi.com
Long-term, high-intensity exercise can trigger stress response pathways in multiple organs,
including the heart and lungs, gastrointestinal tract, skeletal muscle, and neuroendocrine …

Physical activity, sedentary time and sleep duration: Associations with body composition in 10–12-year-old Estonian schoolchildren

EM Riso, M Kull, K Mooses, J Jürimäe - BMC Public Health, 2018 - Springer
Background Physical activity, sedentary time, and sleep duration have been associated with
body composition among children. The purpose of the present study was to assess the …