AGE-RAGE synergy influences programmed cell death signaling to promote cancer
Advanced glycation end products (AGEs) are formed as a result of non-enzymatic reaction
between the free reducing sugars and proteins, lipids, or nucleic acids. AGEs are …
between the free reducing sugars and proteins, lipids, or nucleic acids. AGEs are …
RAGE and its ligands: from pathogenesis to therapeutics
Receptor for advanced glycation end products (RAGE) is an immunoglobulin-like receptor
present on cell surface. RAGE binds to an array of structurally diverse ligands, acts as a …
present on cell surface. RAGE binds to an array of structurally diverse ligands, acts as a …
RAGE expression in tumor-associated macrophages promotes angiogenesis in glioma
X Chen, L Zhang, IY Zhang, J Liang, H Wang… - Cancer research, 2014 - AACR
Interaction of RAGE (the receptor for advanced glycation endproducts) with its ligands can
promote tumor progression, invasion, and angiogenesis. Although blocking RAGE signaling …
promote tumor progression, invasion, and angiogenesis. Although blocking RAGE signaling …
Role of receptor for advanced glycation end products (RAGE) and its ligands in cancer risk
S Yamagishi, T Matsui, K Fukami - Rejuvenation research, 2015 - liebertpub.com
Reducing sugars can react non-enzymatically with the amino groups of proteins, lipids, and
nucleic acids to initiate a complex series of rearrangements and dehydrations, and then to …
nucleic acids to initiate a complex series of rearrangements and dehydrations, and then to …
Zuojin Pill attenuates Helicobacter pylori-induced chronic atrophic gastritis in rats and improves gastric epithelial cells function in GES-1 cells
J Wen, S Wu, X Ma, Y Zhao - Journal of ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance Zuojin pill (ZJP), a classical Chinese medicine formula,
has been widely applied in Chinese clinical practice for the treatment of gastric injury such …
has been widely applied in Chinese clinical practice for the treatment of gastric injury such …
Hyperglycemia-induced aberrant cell proliferation; a metabolic challenge mediated by protein O-GlcNAc modification
Chronic hyperglycemia has been associated with an increased prevalence of pathological
conditions including cardiovascular disease, cancer, or various disorders of the immune …
conditions including cardiovascular disease, cancer, or various disorders of the immune …
[HTML][HTML] Contributions of the receptor for advanced glycation end products axis activation in gastric cancer
Compelling shreds of evidence derived from both clinical and experimental research have
demonstrated the crucial contribution of receptor for advanced glycation end products …
demonstrated the crucial contribution of receptor for advanced glycation end products …
SOSTDC1 inhibits follicular thyroid cancer cell proliferation, migration, and EMT via suppressing PI3K/Akt and MAPK/Erk signaling pathways
Q Zhou, J Chen, J Feng, Y Xu, W Zheng… - Molecular and cellular …, 2017 - Springer
The sclerostin domain containing protein 1 (SOSTDC1) is a cell signaling regulator involved
in cell physiology and pathology. SOSTDC1 is known to have a suppressive effect on certain …
in cell physiology and pathology. SOSTDC1 is known to have a suppressive effect on certain …
Long non‐coding rna ager‐1 functionally upregulates the innate immunity gene ager and approximates its anti‐tumor effect in lung cancer
Z Pan, L Liu, W Nie, S Miggin, F Qiu… - Molecular …, 2018 - Wiley Online Library
Little is known about long non‐coding RNA (lncRNA) related to innate immunity in lung
cancer. The advanced glycosylation end‐product specific receptor (AGER) belongs to the …
cancer. The advanced glycosylation end‐product specific receptor (AGER) belongs to the …
Overexpression of the receptor for advanced glycation endproducts (RAGE) is associated with poor prognosis in gastric cancer
D Wang, T Li, G Ye, Z Shen, Y Hu, T Mou, J Yu, S Li… - PloS one, 2015 - journals.plos.org
Background The receptor for advanced glycation endproducts (RAGE) is an oncogenic
multidisciplinary trans-membranous receptor, which is overexpressed in multiple human …
multidisciplinary trans-membranous receptor, which is overexpressed in multiple human …