[HTML][HTML] Role of the endothelium in inflammatory bowel diseases

WE Cromer, JM Mathis, DN Granger… - World journal of …, 2011 - ncbi.nlm.nih.gov
Inflammatory bowel diseases (IBD) are a complex group of diseases involving alterations in
mucosal immunity and gastrointestinal physiology during both initiation and progressive …

Pathogenic angiogenesis in IBD and experimental colitis: new ideas and therapeutic avenues

JH Chidlow Jr, D Shukla… - American Journal of …, 2007 - journals.physiology.org
Angiogenesis is now understood to play a major role in the pathology of chronic
inflammatory diseases and is indicated to exacerbate disease pathology. Recent evidence …

Evidence of endothelial dysfunction in patients with inflammatory bowel disease

I Roifman, YC Sun, JP Fedwick, R Panaccione… - Clinical …, 2009 - Elsevier
BACKGROUND & AIMS: Chronic inflammation has a major role in the development and
propagation of endothelial dysfunction, which can lead to coronary artery disease …

6-Gingerol modulates proinflammatory responses in dextran sodium sulfate (DSS)-treated Caco-2 cells and experimental colitis in mice through adenosine …

KW Chang, CY Kuo - Food & function, 2015 - pubs.rsc.org
Background: 6-gingerol has been reported to have anti-inflammatory effects in different
experimental settings. The present study aimed at evaluating the effect of 6-gingerol on …

Irisin Stimulates the Release of CXCL1 From Differentiating Human Subcutaneous and Deep-Neck Derived Adipocytes via Upregulation of NFκB Pathway

A Shaw, BB Tóth, R Király, R Arianti… - Frontiers in cell and …, 2021 - frontiersin.org
Thermogenic brown and beige adipocytes might open up new strategies in combating
obesity. Recent studies in rodents and humans have indicated that these adipocytes release …

A single conformational transglutaminase 2 epitope contributed by three domains is critical for celiac antibody binding and effects

Z Simon-Vecsei, R Király, P Bagossi… - Proceedings of the …, 2012 - National Acad Sciences
The multifunctional, protein cross-linking transglutaminase 2 (TG2) is the main autoantigen
in celiac disease, an autoimmune disorder with defined etiology. Glutamine-rich gliadin …

Reduced endothelial progenitor cell number and function in inflammatory bowel disease: a possible link to the pathogenesis

A Garolla, R D'incà, D Checchin, A Biagioli… - Official journal of the …, 2009 - journals.lww.com
OBJECTIVES: Circulating endothelial progenitor cells (EPCs) are essential for endothelial
repair and vascular healing. Patients with inflammatory bowel disease (IBD) may suffer from …

Interplay of myosin phosphatase and protein phosphatase-2A in the regulation of endothelial nitric-oxide synthase phosphorylation and nitric oxide production

R Bátori, B Bécsi, D Nagy, Z Kónya, C Hegedűs… - Scientific reports, 2017 - nature.com
The inhibitory phosphorylation of endothelial nitric oxide (NO) synthase (eNOS) at Thr497
(eNOSpThr497) by protein kinase C or RhoA-activated kinase is a major regulatory …

Vessel Wall‐Derived Mesenchymal Stromal Cells Share Similar Differentiation Potential and Immunomodulatory Properties with Bone Marrow‐Derived Stromal Cells

Z Veréb, A Mázló, A Szabó, S Póliska… - Stem Cells …, 2020 - Wiley Online Library
Purpose. This study is aimed at investigating the phenotype, differentiation potential,
immunomodulatory properties, and responsiveness of saphenous vein vessel wall‐derived …

Functional significance of hsp90 complexes with NOS and sGC in endothelial cells

G Antonova, H Lichtenbeld, T Xia… - Clinical …, 2007 - content.iospress.com
Although the existence of hsp90–NOS and hsp90–sGC complexes is now firmly established,
their role in many pathophysiological processes remain unclear. These complexes may …