Sleep deprivation and neurological disorders

M Bishir, A Bhat, MM Essa, O Ekpo… - BioMed research …, 2020 - Wiley Online Library
Sleep plays an important role in maintaining neuronal circuitry, signalling and helps
maintain overall health and wellbeing. Sleep deprivation (SD) disturbs the circadian …

Physiology of astroglia

A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Norepinephrine modulates calcium dynamics in cortical oligodendrocyte precursor cells promoting proliferation during arousal in mice

TY Lu, P Hanumaihgari, ET Hsu, A Agarwal… - Nature …, 2023 - nature.com
Oligodendrocytes, the myelinating cells of the central nervous system (CNS), are generated
from oligodendrocyte precursor cells (OPCs) that express neurotransmitter receptors …

Ultrastructural evidence for synaptic scaling across the wake/sleep cycle

L De Vivo, M Bellesi, W Marshall, EA Bushong… - Science, 2017 - science.org
It is assumed that synaptic strengthening and weakening balance throughout learning to
avoid runaway potentiation and memory interference. However, energetic and informational …

[PDF][PDF] White matter plasticity in the adult brain

C Sampaio-Baptista, H Johansen-Berg - Neuron, 2017 - cell.com
The study of brain plasticity has tended to focus on the synapse, where well-described
activity-dependent mechanisms are known to play a key role in learning and memory …

[PDF][PDF] Sleep and the price of plasticity: from synaptic and cellular homeostasis to memory consolidation and integration

G Tononi, C Cirelli - Neuron, 2014 - cell.com
Sleep is universal, tightly regulated, and its loss impairs cognition. But why does the brain
need to disconnect from the environment for hours every day? The synaptic homeostasis …

Oligodendrocyte development and plasticity

DE Bergles, WD Richardson - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
Oligodendrocyte precursor cells (OPCs) originate in the ventricular zones (VZs) of the brain
and spinal cord and migrate throughout the developing central nervous system (CNS) …

Sleep loss promotes astrocytic phagocytosis and microglial activation in mouse cerebral cortex

M Bellesi, L de Vivo, M Chini, F Gilli… - Journal of …, 2017 - Soc Neuroscience
We previously found that Mertk and its ligand Gas6, astrocytic genes involved in
phagocytosis, are upregulated after acute sleep deprivation. These results suggested that …

[HTML][HTML] Systematic review of sleep disturbances and circadian sleep desynchronization in autism spectrum disorder: toward an integrative model of a self-reinforcing …

C Carmassi, L Palagini, D Caruso, I Masci… - Frontiers in …, 2019 - frontiersin.org
Background: A compelling number of studies, conducted in both children and adults, have
reported an association between sleep disturbances/circadian sleep alterations and autism …

[HTML][HTML] Functions and mechanisms of sleep

MR Zielinski, JT McKenna, RW McCarley - AIMS neuroscience, 2016 - ncbi.nlm.nih.gov
Sleep is a complex physiological process that is regulated globally, regionally, and locally
by both cellular and molecular mechanisms. It occurs to some extent in all animals, although …