[HTML][HTML] Redefining chronic viral infection

HW Virgin, EJ Wherry, R Ahmed - Cell, 2009 - cell.com
Viruses that cause chronic infection constitute a stable but little-recognized part of our
metagenome: our virome. Ongoing immune responses hold these chronic viruses at bay …

Treating viral hepatitis C: efficacy, side effects, and complications

MP Manns, H Wedemeyer, M Cornberg - Gut, 2006 - gut.bmj.com
The treatment of hepatitis C has dramatically improved over the past decade. Unlike any
other chronic viral infection, a significant proportion of patients with chronic hepatitis C can …

Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection

rgp120 HIV Vaccine Study Group - The Journal of infectious …, 2005 - academic.oup.com
Background A vaccine is needed to prevent human immunodeficiency virus type 1 (HIV-1)
infection Methods A double-blind, randomized trial of a recombinant HIV-1 envelope …

[HTML][HTML] Protective microbiota: from localized to long-reaching co-immunity

L Chiu, T Bazin, ME Truchetet… - Frontiers in …, 2017 - frontiersin.org
Resident microbiota do not just shape host immunity, they can also contribute to host
protection against pathogens and infectious diseases. Previous reviews of the protective …

No one is naive: the significance of heterologous T-cell immunity

RM Welsh, LK Selin - Nature Reviews Immunology, 2002 - nature.com
Memory T cells that are specific for one virus can become activated during infection with an
unrelated heterologous virus, and might have roles in protective immunity and …

[HTML][HTML] The virome in host health and disease

K Cadwell - Immunity, 2015 - cell.com
The mammalian virome includes diverse commensal and pathogenic viruses that evoke a
broad range of immune responses from the host. Sustained viral immunomodulation is …

CD4 T-lymphocyte recovery in individuals with advanced HIV-1 infection receiving potent antiretroviral therapy for 4 years: the Swiss HIV Cohort Study

GR Kaufmann, L Perrin, G Pantaleo… - Archives of internal …, 2003 - jamanetwork.com
Background Highly active antiretroviral therapy (HAART) for human immunodeficiency virus
(HIV)-1 infection allows recovery of CD4 T lymphocytes. Few studies have explored the long …

Impracticability of informed consent in the Registry of the Canadian Stroke Network

JV Tu, DJ Willison, FL Silver, J Fang… - … England Journal of …, 2004 - Mass Medical Soc
Background Government legislators and research ethics boards in some jurisdictions
require all patients to give written informed consent before enrollment in clinical registries …

What is a pathogen? Toward a process view of host-parasite interactions

PO Méthot, S Alizon - Virulence, 2014 - Taylor & Francis
Until quite recently and since the late 19th century, medical microbiology has been based on
the assumption that some micro-organisms are pathogens and others are not. This binary …

Hepatitis C and progression of HIV disease

MS Sulkowski, RD Moore, SH Mehta, RE Chaisson… - Jama, 2002 - jamanetwork.com
ContextConflicting reports exist regarding the effect of hepatitis C virus (HCV) on the
progression of human immunodeficiency virus (HIV) disease. ObjectiveTo assess the effect …