Emerging pharmacotherapy of tinnitus

B Langguth, R Salvi, AB Elgoyhen - Expert opinion on emerging …, 2009 - Taylor & Francis
Tinnitus, the perception of sound in the absence of an auditory stimulus, is perceived by
about 1 in 10 adults, and for at least 1 in 100, tinnitus severely affects their quality of life …

[图书][B] Chitin, chitosan, oligosaccharides and their derivatives: biological activities and applications

SK Kim - 2010 - books.google.com
Providing comprehensive coverage of the biological activities and industrial applications of
Chitin, Chitosan, oligosaccharides, and their derivatives, this book presents a balance of …

The relationship between autism spectrum disorder and melatonin during fetal development

Y Jin, J Choi, J Won, Y Hong - Molecules, 2018 - mdpi.com
The aim of this review is to clarify the interrelationship between melatonin and autism
spectrum disorder (ASD) during fetal development. ASD refers to a diverse range of …

Antioxidative effects of melatonin on kinetics, microscopic and oxidative parameters of cryopreserved bull spermatozoa

I Ashrafi, H Kohram, FF Ardabili - Animal Reproduction Science, 2013 - Elsevier
Reactive oxygen species generated during the freeze–thawing process may reduce sperm
quality. This study evaluates the effects of melatonin supplementation as an antioxidant in …

Molecular mechanisms of melatonin anticancer effects

SM Hill, T Frasch, S Xiang, L Yuan… - Integrative cancer …, 2009 - journals.sagepub.com
The authors have shown that, via activation of its MT1 receptor, melatonin modulates the
transcriptional activity of various nuclear receptors and the proliferation of both ERα+ and …

The in vitro effects of melatonin on human sperm function and its scavenging activities on NO and ROS

SS Du Plessis, K Hagenaar, F Lampiao - Andrologia, 2010 - Wiley Online Library
Various systems of antioxidants exist endogenously in the body to help protect it against free
radical damage by scavenging excessive ROS and RNS. Melatonin, a hormone secreted by …

Endogenous antioxidants and radical scavengers

AM Rizzo, P Berselli, S Zava, G Montorfano… - Bio-farms for …, 2010 - Springer
All living organisms are constantly exposed to oxidant agents deriving from both endog-
enous and exogenous sources capable to modify biomolecules and induce damages. Free …

Regulating the balance between the kynurenine and serotonin pathways of tryptophan metabolism

Y Li, N Hu, D Yang, G Oxenkrug, Q Yang - The FEBS journal, 2017 - Wiley Online Library
Tryptophan is metabolized along the kynurenine and serotonin pathways, resulting in
formation of kynurenine metabolites, neuroactive serotonin and melatonin. Each pathway is …

[HTML][HTML] Melatonin induces cell apoptosis in AGS cells through the activation of JNK and P38 MAPK and the suppression of nuclear factor-kappa B: A novel …

W Li, M Fan, Y Chen, Q Zhao, C Song, Y Yan… - Cellular Physiology and …, 2015 - karger.com
Background/Aims: Melatonin, synthesized by the pineal gland and released into the blood,
appears to have antitumour properties; however, the mechanisms of its anti-cancer effects …

Mycorrhizal fungi regulate daily rhythm of circadian clock in trifoliate orange under drought stress

YE Ding, YN Zou, QS Wu, K Kuča - Tree Physiology, 2022 - academic.oup.com
The circadian rhythm of plants is associated with stress responses; however, it is not clear
whether increased host plant drought tolerance by arbuscular mycorrhizal fungi (AMF) is …