Peptide-based drug-delivery systems in biotechnological applications: recent advances and perspectives
D Tesauro, A Accardo, C Diaferia, V Milano, J Guillon… - Molecules, 2019 - mdpi.com
Peptides of natural and synthetic sources are compounds operating in a wide range of
biological interactions. They play a key role in biotechnological applications as both …
biological interactions. They play a key role in biotechnological applications as both …
Pharmacokinetics and in vivo drug release rates in liposomal nanocarrier development
DC Drummond, CO Noble, ME Hayes, JW Park… - Journal of …, 2008 - Elsevier
Liposomes represent a widely varied and malleable class of drug carriers generally
characterized by the presence of one or more amphiphile bilayers enclosing an interior …
characterized by the presence of one or more amphiphile bilayers enclosing an interior …
Synthesis of biomolecule‐modified mesoporous silica nanoparticles for targeted hydrophobic drug delivery to cancer cells
DP Ferris, J Lu, C Gothard, R Yanes, CR Thomas… - Small, 2011 - Wiley Online Library
Synthetic methodologies integrating hydrophobic drug delivery and biomolecular targeting
with mesoporous silica nanoparticles are described. Transferrin and cyclic‐RGD peptides …
with mesoporous silica nanoparticles are described. Transferrin and cyclic‐RGD peptides …
A biomimetic microfluidic tumor microenvironment platform mimicking the EPR effect for rapid screening of drug delivery systems
Real-time monitoring of tumor drug delivery in vivo is a daunting challenge due to the
heterogeneity and complexity of the tumor microenvironment. In this study, we developed a …
heterogeneity and complexity of the tumor microenvironment. In this study, we developed a …
Anti-cancer therapies targeting the tumor stroma
For anti-tumor therapy different strategies have been employed, eg, radiotherapy,
chemotherapy, or immunotherapy. Notably, these approaches do not only address the tumor …
chemotherapy, or immunotherapy. Notably, these approaches do not only address the tumor …
The development of site-specific drug delivery nanocarriers based on receptor mediation
Since they were first reported in 1980, site-specific drug delivery nanocarriers have
progressed greatly with the development of nanotechnology and biotechnology, especially …
progressed greatly with the development of nanotechnology and biotechnology, especially …
Radionuclide carriers for targeting of cancer
S Sofou - International journal of nanomedicine, 2008 - Taylor & Francis
This review describes strategies for the delivery of therapeutic radionuclides to tumor sites.
Therapeutic approaches are summarized in terms of tumor location in the body, and tumor …
Therapeutic approaches are summarized in terms of tumor location in the body, and tumor …
Application of pharmacokinetic and pharmacodynamic analysis to the development of liposomal formulations for oncology
S Ait-Oudhia, DE Mager, RM Straubinger - Pharmaceutics, 2014 - mdpi.com
Liposomal formulations of anticancer agents have been developed to prolong drug
circulating lifetime, enhance anti-tumor efficacy by increasing tumor drug deposition, and …
circulating lifetime, enhance anti-tumor efficacy by increasing tumor drug deposition, and …
Immunoliposomes
E Paszko, MO Senge - Current medicinal chemistry, 2012 - ingentaconnect.com
Since their discovery by Bangham about 50 years ago, liposomes have become promising
tools in drug delivery systems. This has increased the therapeutic index of many drugs, and …
tools in drug delivery systems. This has increased the therapeutic index of many drugs, and …
Targeted multidrug delivery system to overcome chemoresistance in breast cancer
Chemotherapy has been widely used in breast cancer patients to reduce tumor size.
However, most anticancer agents cannot differentiate between cancerous and normal cells …
However, most anticancer agents cannot differentiate between cancerous and normal cells …