Ectonucleotidase inhibitors: targeting signaling pathways for therapeutic advancement—an in-depth review
RH Sharafat, A Saeed - Purinergic Signalling, 2024 - Springer
Ectonucleotidase inhibitors are a family of pharmacological drugs that, by selectively
targeting ectonucleotidases, are essential in altering purinergic signaling pathways. The …
targeting ectonucleotidases, are essential in altering purinergic signaling pathways. The …
Plant-derived strategies to fight against severe acute respiratory syndrome coronavirus 2
W Li, T Ding, H Chang, Y Peng, J Li, X Liang… - European Journal of …, 2024 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic has caused an
unprecedented crisis, which has been exacerbated because specific drugs and treatments …
unprecedented crisis, which has been exacerbated because specific drugs and treatments …
Algal macromolecular mediated synthesis of nanoparticles for their application against citrus canker for food security
H Waqif, N Munir, MA Farrukh, M Hasnain… - International Journal of …, 2024 - Elsevier
Citrus canker is a disease of economic importance and there are limited biocontrol agents
available to mitigate it in an integrated manner. This study was conducted to combat citrus …
available to mitigate it in an integrated manner. This study was conducted to combat citrus …
Synthesis and biological research of new imidazolone-sulphonamide-pyrimidine hybrids as potential EGFR-TK inhibitors and apoptosis-inducing agents
Development of new effective EGFR-targeted antitumor agents is needed because of their
clinical significance. A new series of imidazolone-sulphonamide-pyrimidine hybrids was …
clinical significance. A new series of imidazolone-sulphonamide-pyrimidine hybrids was …
Novel sulfonyl hydrazide based β-carboline derivatives as potential α-glucosidase inhibitors: design, synthesis, and biological evaluation
J Sun, D Xiao, M Lang, X Xu - Molecular Diversity, 2024 - Springer
A series of novel sulfonyl hydrazide based β-carboline derivatives (SX1–SX32) were
designed and synthesized, and their structures were characterized on NMR and HRMS …
designed and synthesized, and their structures were characterized on NMR and HRMS …
Design, synthesis, docking, ADMET and anticancer evaluations of N-alkyl substituted iodoquinazoline derivatives as dual VEGFR-2 and EGFR inhibitors
Fifteen new 1-alkyl-6-iodoquinazoline derivatives 5a–d to 9a–e were designed and
synthesized and their anticancer activities were evaluated against HepG2, MCF-7, HCT116 …
synthesized and their anticancer activities were evaluated against HepG2, MCF-7, HCT116 …
Green and rapid and instrumental one-pot method for the synthesis of imidazolines having potential anti-SARS-CoV-2 main protease activity
Abstract The Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) is
responsible for ongoing epidemics in humans and some other mammals and has been …
responsible for ongoing epidemics in humans and some other mammals and has been …
Evaluation of antibacterial, cytotoxicity, and apoptosis activity of novel chromene-sulfonamide hybrids synthesized under solvent-free conditions and 3D-QSAR …
In this study, eleven novel chromene sulfonamide hybrids were synthesized by a convenient
method in accordance with green chemistry. At first, chromene derivatives (1–9a) were …
method in accordance with green chemistry. At first, chromene derivatives (1–9a) were …
High Inhibition for a CoII Tetrazole Bi‐pyrazole Dinuclear Complex against Fusarium Oxysporum f. sp. Albedinis
New coordination compounds made of two novel tetrazole and C, N‐bipyrazole ligands, 2‐
(3, 5, 5′‐trimethyl‐1′ H‐[1, 3′‐bipyrazol]‐1′‐yl) acetonitrile (L1), and 1′‐((1H‐tetrazol …
(3, 5, 5′‐trimethyl‐1′ H‐[1, 3′‐bipyrazol]‐1′‐yl) acetonitrile (L1), and 1′‐((1H‐tetrazol …
[HTML][HTML] Synthesis, Identification, and anti-cancer Evaluation of Some heterocyclic Chitosan-Thiosemicarbazones compounds and their nickle (II) complexes
MO Mohammed, HMM Alkubaisi, NQ Haj - Results in Chemistry, 2024 - Elsevier
Chitosan (CS) a chemical substance taken from the shells of sea creatures that has various
uses in industry, farming, and medicine, for example in medical dressings. Its derivatives …
uses in industry, farming, and medicine, for example in medical dressings. Its derivatives …