Torpor and hibernation are powerful strategies enabling animals to survive periods of low
resource availability. The state of torpor results from an active and drastic reduction of an …

Cold ischemia-reperfusion injury (IRI) is an inevitable and unresolved problem that poses a
great challenge in solid organ transplantation (SOT). It represents a major factor that …

Introduction Alpha-lipoic acid (ALA) is a licensed drug for the treatment of diabetic
neuropathy. We recently reported that it also improves diabetic cardiomyopathy (DCM) in …

Introduction We previously reported that alpha-lipoic acid (ALA) supplementation protects
against progression of diabetic kidney disease (DKD). In this study, we aim to investigate …

Hibernation is a state of reduced metabolic activity used by some animals to survive in harsh
environmental conditions. The idea of exploiting hibernation for space exploration has been …

Future human space missions to Mars and beyond may be realized for different research,
economic, political or survival reasons. Since space remains a hazardous environment for …

Ischemia-reperfusion injury (IRI), a pathological condition resulting from prolonged
cessation and subsequent restoration of blood flow to a tissue, is an inevitable consequence …

In mammals, torpor/hibernation is a state that is characterized by an active reduction in
metabolic rate followed by a progressive decrease in body temperature. Torpor was …

The global donor kidney shortage crisis has necessitated the use of suboptimal kidneys from
donors-after-cardiac-death (DCD). Using an ex vivo porcine model of DCD kidney …

Acute lung injury (ALI) caused by septic stimuli is still a major problem in critical care
patients. We have shown previously that hydrogen sulfide (H 2 S) mediates anti …