The endocrine function of human placenta: an overview
MA Costa - Reproductive biomedicine online, 2016 - Elsevier
During pregnancy, several tightly coordinated and regulated processes take place to enable
proper fetal development and gestational success. The formation and development of the …
proper fetal development and gestational success. The formation and development of the …
Reproductive functions of Kisspeptin/KISS1R Systems in the Periphery
Y Cao, Z Li, W Jiang, Y Ling, H Kuang - Reproductive Biology and …, 2019 - Springer
Kisspeptin and its G protein-coupled receptor KISS1R play key roles in mammalian
reproduction due to their involvement in the onset of puberty and control of the hypothalamic …
reproduction due to their involvement in the onset of puberty and control of the hypothalamic …
Thyroid hormone regulated genes in cerebral cortex development
J Bernal - Journal of Endocrinology, 2017 - joe.bioscientifica.com
Endothelial dysfunction is an important risk factor for cardiovascular disease, and it
represents the initial step in the pathogenesis of atherosclerosis. Failure to protect against …
represents the initial step in the pathogenesis of atherosclerosis. Failure to protect against …
Potential roles for the kisspeptin/kisspeptin receptor system in implantation and placentation
BACKGROUND Initially identified as suppressors of metastasis in various types of cancer,
kisspeptins are a family of neuropeptides that are key regulators of the mammalian …
kisspeptins are a family of neuropeptides that are key regulators of the mammalian …
Induced pluripotent stem cell model of pulmonary arterial hypertension reveals novel gene expression and patient specificity
Rationale: Idiopathic or heritable pulmonary arterial hypertension is characterized by loss
and obliteration of lung vasculature. Endothelial cell dysfunction is pivotal to the …
and obliteration of lung vasculature. Endothelial cell dysfunction is pivotal to the …
EGF stimulates human trophoblast cell invasion by downregulating ID3-mediated KISS1 expression
L Fang, Y Gao, Z Wang, Y Li, Y Yan, Z Wu… - Cell Communication and …, 2021 - Springer
Background During pregnancy, trophoblast cell invasion needs to be finely controlled.
Aberrant trophoblast cell invasion is associated with placental diseases. Epidermal growth …
Aberrant trophoblast cell invasion is associated with placental diseases. Epidermal growth …
Peripheral action of kisspeptin at reproductive tissues—role in ovarian function and embryo implantation and relevance to assisted reproductive technology in …
MJ D'Occhio, G Campanile… - Biology of …, 2020 - academic.oup.com
Kisspeptin (KISS1) is encoded by the KISS1 gene and was initially found to be a repressor
of metastasis. Natural mutations in the KISS1 receptor gene (KISS1R) were subsequently …
of metastasis. Natural mutations in the KISS1 receptor gene (KISS1R) were subsequently …
TGF-β1 inhibits human trophoblast cell invasion by upregulating kisspeptin expression through ERK1/2 but not SMAD signaling pathway
L Fang, Y Yan, Y Gao, Z Wu, Z Wang, S Yang… - Reproductive Biology …, 2022 - Springer
Background Tightly regulation of extravillous cytotrophoblast (EVT) cell invasion is critical for
the placentation and establishment of a successful pregnancy. Insufficient EVT cell invasion …
the placentation and establishment of a successful pregnancy. Insufficient EVT cell invasion …
Kisspeptin in the prediction of pregnancy complications
J Tsoutsouki, B Patel, AN Comninos… - Frontiers in …, 2022 - frontiersin.org
Kisspeptin and its receptor are central to reproductive health acting as key regulators of the
reproductive endocrine axis in humans. Kisspeptin is most widely recognised as a regulator …
reproductive endocrine axis in humans. Kisspeptin is most widely recognised as a regulator …
Kisspeptin as a new serum biomarker to discriminate miscarriage from viable intrauterine pregnancy
C Sullivan-Pyke, DJ Haisenleder, S Senapati… - Fertility and sterility, 2018 - Elsevier
Objective To validate the ability of serum kisspeptin-54 to discriminate between first-trimester
viable pregnancies and miscarriages. Design Case-control study. Setting Academic medical …
viable pregnancies and miscarriages. Design Case-control study. Setting Academic medical …