Spinal cord stimulation: neurophysiological and neurochemical mechanisms of action
Y Guan - Current pain and headache reports, 2012 - Springer
Chronic neuropathic pain can significantly reduce quality of life and place an economic
burden on individuals and society. Spinal cord stimulation (SCS) is an alternative approach …
burden on individuals and society. Spinal cord stimulation (SCS) is an alternative approach …
Experimental spinal cord stimulation and neuropathic pain: mechanism of action, technical aspects, and effectiveness
H Smits, M van Kleef, J Holsheimer… - Pain Practice, 2013 - Wiley Online Library
Spinal cord stimulation (SCS) is a valuable treatment for chronic intractable neuropathic
pain. Although SCS has gone through a technological revolution over the last four decades …
pain. Although SCS has gone through a technological revolution over the last four decades …
Efficacy of kilohertz-frequency and conventional spinal cord stimulation in rat models of different pain conditions
Z Song, H Viisanen, BA Meyerson, A Pertovaara… - … : Technology at the …, 2014 - Elsevier
Objectives: The aim was to compare the effects of high-frequency spinal cord stimulation (HF-
SCS) at subparesthetic intensity with conventional SCS in rat models of different types of …
SCS) at subparesthetic intensity with conventional SCS in rat models of different types of …
Prunella vulgaris L. active components and their hypoglycemic and antinociceptive effects in alloxan-induced diabetic mice
K Raafat, M Wurglics, M Schubert-Zsilavecz - Biomedicine & …, 2016 - Elsevier
Abstract Prunella vulgaris L.(Lamiaceae)(PV) is a herbaceous plant traditionally utilized in
management of diabetes and it has immunomodulatory activity. In this study, acute and …
management of diabetes and it has immunomodulatory activity. In this study, acute and …
Burst and tonic spinal cord stimulation both activate spinal GABAergic mechanisms to attenuate pain in a rat model of chronic neuropathic pain
KPV Meuwissen, LE de Vries, JW Gu, TC Zhang… - Pain …, 2020 - Wiley Online Library
Background Experimental and clinical studies have shown that tonic spinal cord stimulation
(SCS) releases gamma‐aminobutyric acid (GABA) in the spinal dorsal horn. Recently, it was …
(SCS) releases gamma‐aminobutyric acid (GABA) in the spinal dorsal horn. Recently, it was …
A review of clinical data on salvage therapy in spinal cord stimulation
RD Reddy, R Moheimani, GY Gregory… - … : Technology at the …, 2020 - Elsevier
Background Since its introduction in 1967, neuromodulation through spinal cord stimulation
(SCS) or dorsal root ganglion stimulation (DRGs) has advanced significantly in both the …
(SCS) or dorsal root ganglion stimulation (DRGs) has advanced significantly in both the …
Differential GABAergic disinhibition during the development of painful peripheral neuropathy
SP Janssen, M Truin, M Van Kleef, EA Joosten - Neuroscience, 2011 - Elsevier
An impaired spinal GABAergic inhibitory function is known to be pivotal in neuropathic pain
(NPP). At present, data concerning time-dependent alterations within the GABAergic system …
(NPP). At present, data concerning time-dependent alterations within the GABAergic system …
Inhibition of 2-AG hydrolysis alleviates posttraumatic headache attributed to mild traumatic brain injury
J Wen, M Tanaka, Y Zhang - The Journal of Headache and Pain, 2024 - Springer
Background Posttraumatic headache (PTH) is a common and debilitating symptom following
repetitive mild traumatic brain injury (rmTBI), and it mainly resembles a migraine-like …
repetitive mild traumatic brain injury (rmTBI), and it mainly resembles a migraine-like …
Decreased intracellular GABA levels contribute to spinal cord stimulation-induced analgesia in rats suffering from painful peripheral neuropathy: The role of KCC2 and …
SP Janssen, S Gerard, ME Raijmakers, M Truin… - Neurochemistry …, 2012 - Elsevier
Elevated spinal extracellular γ-aminobutyric acid (GABA) levels have been described during
spinal cord stimulation (SCS)-induced analgesia in experimental chronic peripheral …
spinal cord stimulation (SCS)-induced analgesia in experimental chronic peripheral …
Epidural spinal cord stimulation promotes motor functional recovery by enhancing oligodendrocyte survival and differentiation and by protecting myelin after spinal …
G Li, ZK Fan, GF Gu, ZQ Jia, QQ Zhang, JY Dai… - Neuroscience …, 2020 - Springer
Epidural spinal cord stimulation (ESCS) markedly improves motor and sensory function after
spinal cord injury (SCI), but the underlying mechanisms are unclear. Here, we investigated …
spinal cord injury (SCI), but the underlying mechanisms are unclear. Here, we investigated …