[HTML][HTML] Amino acids in the regulation of aging and aging-related diseases
CA Canfield, PC Bradshaw - Translational Medicine of Aging, 2019 - Elsevier
Amino acids are the building blocks of protein, but also play important cellular signaling
roles. The mechanisms through which altered levels of many amino acids are sensed and …
roles. The mechanisms through which altered levels of many amino acids are sensed and …
[HTML][HTML] Carnosine and beta-alanine supplementation in human medicine: narrative review and critical assessment
O Cesak, J Vostalova, A Vidlar, P Bastlova… - Nutrients, 2023 - mdpi.com
The dipeptide carnosine is a physiologically important molecule in the human body,
commonly found in skeletal muscle and brain tissue. Beta-alanine is a limiting precursor of …
commonly found in skeletal muscle and brain tissue. Beta-alanine is a limiting precursor of …
[HTML][HTML] Anti-cancer actions of carnosine and the restoration of normal cellular homeostasis
MD Turner, C Sale, AC Garner, AR Hipkiss - Biochimica et Biophysica Acta …, 2021 - Elsevier
Carnosine is a naturally occurring dipeptide found in meat. Alternatively it can be formed
through synthesis from the amino acids, β-alanine and L-histidine. Carnosine has long been …
through synthesis from the amino acids, β-alanine and L-histidine. Carnosine has long been …
[HTML][HTML] Non-enzymatic molecular damage as a prototypic driver of aging
A Golubev, AD Hanson, VN Gladyshev - Journal of Biological Chemistry, 2017 - ASBMB
The chemical potentialities of metabolites far exceed metabolic requirements. The required
potentialities are realized mostly through enzymatic catalysis. The rest are realized …
potentialities are realized mostly through enzymatic catalysis. The rest are realized …
Effects of combined carnosine and ultra-high pressure on the inhibition of fishy off-odor of snakehead fillets and the possible mechanism
L Sun, J Lv, Y Liu, M Zang, P Li, D Wang, Y Zhu, W Xu - Food Chemistry, 2022 - Elsevier
The effects of combined application of ultra-high pressure (300 Mpa, 900 s) and carnosine
on the inhibition of fishy off-odor from snakehead meat were investigated. Results showed …
on the inhibition of fishy off-odor from snakehead meat were investigated. Results showed …
Gerontechnological factors affecting successful aging of elderly
F Özsungur - The Aging Male, 2020 - Taylor & Francis
In this article, the gerontological factors affecting the successful aging of the elderly have
been uncovered, the quality of life and successful aging issues have been related to …
been uncovered, the quality of life and successful aging issues have been related to …
Carnosine decreased oxidation and glycation products in serum and liver of high‐fat diet and low‐dose streptozotocin‐induced diabetic rats
High‐fat diet (HFD) and low‐dose streptozotocin (STZ)‐treated rats provide useful animal
model for type II diabetes mellitus. Oxidative stress and advanced glycation end products …
model for type II diabetes mellitus. Oxidative stress and advanced glycation end products …
Integration of mass spectrometry imaging and machine learning visualizes region-specific age-induced and drug-target metabolic perturbations in the brain
T Vallianatou, R Shariatgorji, A Nilsson… - ACS Chemical …, 2021 - ACS Publications
Detailed metabolic imaging of specific brain regions in early aging may expose
pathophysiological mechanisms and indicate effective neuropharmacological targets in the …
pathophysiological mechanisms and indicate effective neuropharmacological targets in the …
[HTML][HTML] Anti-cancer effects of carnosine—A dipeptide molecule
MD Prakash, S Fraser, JC Boer, M Plebanski… - Molecules, 2021 - mdpi.com
Background: Carnosine is a dipeptide molecule (β-alanyl-l-histidine) with anti-inflammatory,
antioxidant, anti-glycation, and chelating properties. It is used in exercise physiology as a …
antioxidant, anti-glycation, and chelating properties. It is used in exercise physiology as a …
Geroprotective interventions in the 3xTg mouse model of Alzheimer's disease
MM Sonsalla, DW Lamming - Geroscience, 2023 - Springer
Alzheimer's disease (AD) is an age-associated neurodegenerative disease. As the
population ages, the increasing prevalence of AD threatens massive healthcare costs in the …
population ages, the increasing prevalence of AD threatens massive healthcare costs in the …