With the progress of medical technology, biomedical field ushered in the era of big data,
based on which and driven by artificial intelligence technology, computational medicine has …

Background Ivacaftor is the first in a class of drugs, CFTR modulators, that target the
underlying defect in cystic fibrosis (CF). This long-term observational safety study evaluated …

Background Cystic fibrosis (CF) is the most common inherited disease in Caucasians,
affecting around 10,000 individuals in the UK today. Prognosis has improved considerably …

Background Ivacaftor is the first cystic fibrosis transmembrane conductance regulator
(CFTR) modulator demonstrating clinical benefit in patients with cystic fibrosis (CF). As …

Introduction: Cystic fibrosis (CF) remains a life-threatening genetic disease, with few
clinically effective treatment options. Gene therapy and gene editing strategies offer the …

Objective Cystic fibrosis associated liver disease (CFLD) is the third largest cause of
mortality in CF. Our aim was to define the burden of CFLD in the UK using national registry …

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Time-series learning is the bread and butter of data-driven* clinical decision support*, and
the recent explosion in ML research has demonstrated great potential in various healthcare …

Pseudomonas aeruginosa biofilm infections in the cystic fibrosis (CF) lung are highly
resistant to current antimicrobial treatments and are associated with increased mortality …

Globally, chronic respiratory diseases (CRDs), both communicable and noncommunicable,
are among the leading causes of mortality, morbidity, economic and societal burden, and …