Bacterial profile of ocular infections: a systematic review

M Teweldemedhin, H Gebreyesus, AH Atsbaha… - BMC …, 2017 - Springer
Background Bacteria are the major contributor of ocular infections worldwide. Ocular
infections, if left untreated, can damage the structures of the eye with possible blindness and …

Antibiotic resistance in the treatment of Staphylococcus aureus keratitis: a 20-year review

VS Chang, DK Dhaliwal, L Raju, RP Kowalski - Cornea, 2015 - journals.lww.com
Purpose: We compared the resistance patterns of methicillin-resistant Staphylococcus
aureus (MRSA) and methicillin-susceptible Staphylococcus aureus (MSSA) keratitis isolates …

Development and evaluation of chitosan nanoparticles for ocular delivery of tedizolid phosphate

MA Kalam, M Iqbal, A Alshememry, M Alkholief… - Molecules, 2022 - mdpi.com
This study investigates the development of topically applied non-invasive chitosan-
nanoparticles (CSNPs) for ocular delivery of tedizolid phosphate (TZP) for the treatment of …

Augmented efficiency of azithromycin for MRSA ocular infections management: Limonene-based nanostructured lipid carriers in-situ approach

KK Abla, SM Hijazi, MM Mehanna - Journal of Drug Delivery Science and …, 2023 - Elsevier
Staphylococcus aureus (S. aureus) is the main pathogen that leads to serious ocular
infectious disorders such as endophthalmitis and keratitis. A major obstacle in managing …

Vancomycin-loaded niosomes integrated within pH-sensitive in-situ forming gel for treatment of ocular infections while minimizing drug irritation

A Allam, MA El-Mokhtar… - Journal of Pharmacy and …, 2019 - academic.oup.com
Objectives The aim of the current study was to minimize ocular irritation and prolong the
pharmacological action of vancomycin via formulation into nanosized spherical niosomes …

An Eye on Staphylococcus aureus Toxins: Roles in Ocular Damage and Inflammation

R Astley, FC Miller, MH Mursalin, PS Coburn… - Toxins, 2019 - mdpi.com
Staphylococcus aureus (S. aureus) is a common pathogen of the eye, capable of infecting
external tissues such as the tear duct, conjunctiva, and the cornea, as well the inner and …

Photodynamic UVA‐riboflavin bacterial elimination in antibiotic‐resistant bacteria

K Makdoumi, A Bäckman - Clinical & experimental …, 2016 - Wiley Online Library
Background To evaluate the bactericidal effect of clinical ultraviolet A (UVA) settings used in
photoactivated chromophore for infectious keratitis (PACK)‐collagen cross‐linking (CXL) in …

Staphylococcus aureus Keratitis: Incidence, Pathophysiology, Risk Factors and Novel Strategies for Treatment

JW Lee, T Somerville, SB Kaye, V Romano - Journal of Clinical Medicine, 2021 - mdpi.com
Bacterial keratitis is a devastating condition that can rapidly progress to serious
complications if not treated promptly. Certain causative microorganisms such as …

Topical Application of Linezolid–Loaded Chitosan Nanoparticles for the Treatment of Eye Infections

M Alkholief, MA Kalam, AK Alshememry, R Ali… - Nanomaterials, 2023 - mdpi.com
Linezolid (LZ) loaded chitosan–nanoparticles (CSNPs) was developed by the ionic–gelation
method using Tripolyphosphate–sodium as a crosslinker for topical application for the …

Recent development and fighting strategies for lincosamide antibiotic resistance

Y Yang, S Xie, F He, Y Xu, Z Wang… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Lincosamides constitute an important class of antibiotics used against a wide range of
pathogens, including methicillin-resistant Staphylococcus aureus. However, due to the …