1, 2, 3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships
Z Xu, SJ Zhao, Y Liu - European journal of medicinal chemistry, 2019 - Elsevier
Anticancer agents are critical for the cancer treatment, but side effects and the drug
resistance associated with the currently used anticancer agents create an urgent need to …
resistance associated with the currently used anticancer agents create an urgent need to …
Ferrocene-containing hybrids as potential anticancer agents: Current developments, mechanisms of action and structure-activity relationships
Cancer is one of the most fatal threatens to human health throughout the world. The major
challenges in the control and eradication of cancers are the continuous emergency of drug …
challenges in the control and eradication of cancers are the continuous emergency of drug …
Recent accomplishments on the synthetic/biological facets of pharmacologically active 1H-1, 2, 3-triazoles
The continuous demand of medicinally important scaffolds has prompted the synthetic
chemists to identify simple and efficient routes for their synthesis. 1H-1, 2, 3-triazole …
chemists to identify simple and efficient routes for their synthesis. 1H-1, 2, 3-triazole …
Recent advances in bioactive flavonoid hybrids linked by 1, 2, 3-triazole ring obtained by click chemistry
D Pereira, M Pinto, M Correia-da-Silva, H Cidade - Molecules, 2021 - mdpi.com
As a result of the biological activities of natural flavonoids, several synthetic strategies
aiming to obtain analogues with improved potency and/or pharmacokinetic profile have …
aiming to obtain analogues with improved potency and/or pharmacokinetic profile have …
Recent advancements in uracil and 5-fluorouracil hybrids as potential anticancer agents: A review
Cancer is the most dreadful disease and the second main cause of death worldwide. The
continuous developments have been going on in order to design potent molecules such that …
continuous developments have been going on in order to design potent molecules such that …
Therapeutic potential of 1, 2, 3‐triazole hybrids for leukemia treatment
W Yang, B Xuan, X Li, H Si, A Chen - Archiv der Pharmazie, 2022 - Wiley Online Library
Leukemia, a hematological malignancy originating from the bone marrow, is the principal
cancer of childhood. In recent decades, improved remission rates and survival of patients …
cancer of childhood. In recent decades, improved remission rates and survival of patients …
Synthesis and biological evaluations of mono‐and bis‐ferrocene uracil derivatives
Mono‐(3a–3e and 4a–4e) and bis‐ferrocene (5a–5e and 6a–6e) conjugated 5‐substituted
uracil derivatives that are bridged by 1, 2, 3‐triazole linker were synthesized. The impact of …
uracil derivatives that are bridged by 1, 2, 3‐triazole linker were synthesized. The impact of …