Update on coagulase-negative staphylococci—what the clinician should know

R Michels, K Last, SL Becker, C Papan - Microorganisms, 2021 - mdpi.com
Coagulase-negative staphylococci (CoNS) are among the most frequently recovered
bacteria in routine clinical care. Their incidence has steadily increased over the past …

Prolonged use of linezolid in bone and joint infections: a retrospective analysis of adverse effects

K Veerman, J Goosen, K Spijkers… - Journal of …, 2023 - academic.oup.com
Objectives Antibiotic treatment for bone and joint infections generally lasts for 6 weeks or
longer. Linezolid may be a good option for treating bone and joint infections, but there is an …

The novel oxazolidinone TBI-223 is effective in three preclinical mouse models of methicillin-resistant Staphylococcus aureus infection

O Gordon, DA Dikeman, RV Ortines, Y Wang… - Microbiology …, 2022 - Am Soc Microbiol
Staphylococcus aureus is an important cause of various infections in humans, including
bacteremia, skin and soft tissue infections, and infections associated with implanted medical …

[HTML][HTML] Antimicrobials in Orthopedic Infections: Overview of Clinical Perspective and Microbial Resistance

B Huzum, AC Aprotosoaie, O Alexa, PD Sîrbu, B Puha… - Medicina, 2024 - mdpi.com
Orthopedic infections are challenging pathologies that impose a heavy burden on patients
and the healthcare system. Antimicrobial therapy is a critical component of the successful …

Effectiveness and safety of dalbavancin in France: a prospective, multicentre cohort study

J Courjon, E Senneville, HG Illes, P Pavese… - International Journal of …, 2023 - Elsevier
Objectives Dalbavancin is a lipoglycopeptide antibiotic approved for the treatment of acute
bacterial skin and skin structure infections. However, several studies have suggested that it …

From remote to urbanized: Dispersal of antibiotic-resistant bacteria under the aspect of anthropogenic influence

D Gattinger, V Schlenz, T Weil, B Sattler - Science of the Total Environment, 2024 - Elsevier
Antibiotic resistance is a growing global concern, but our understanding of the spread of
resistant bacteria in remote regions remains limited. While some level of intrinsic resistance …

Eradication of Staphylococcus aureus in Implant-Associated Osteomyelitis by an Injectable in situ-Forming Depot Antibiotics Delivery System

AJ Fuglsang-Madsen, NL Henriksen… - The Journal of …, 2024 - academic.oup.com
Abstract Background Bone infections from Staphylococcus aureus are notoriously difficult to
treat and have high recurrence rates. Local antibiotic delivery systems hold the potential to …

Do High Doses of Multiple Antibiotics Loaded into Bone Cement Spacers Improve the Success Rate in Staphylococcal Periprosthetic Joint Infection When Rifampicin …

L Prats-Peinado, T Fernández-Fernández… - Antibiotics, 2024 - mdpi.com
Rifampicin is one of the mainstays in treating staphylococcal prosthetic joint infection (PJI).
However, discontinuation due to intolerance, drug interactions, and adverse events is …

Uncommon Septic Arthritis of the Hip Joint in an Immunocompetent Adult Patient Due to Bacillus pumilus and Paenibacillus barengoltzii Managed with Long-Term …

RS Cismasiu, RM Birlutiu, LL Preoțescu - Pharmaceuticals, 2023 - mdpi.com
The Bacillus and Paenibacillus genera are diverse soil-related bacterial pathogens. In this
case report, we describe, to our knowledge, the first report of septic arthritis in a native hip …

Two-Stage Revision Arthroplasty for Resistant Gram-Positive Periprosthetic Joint Infections Using an Oral Linezolid-Based Antibiotic Regime

L Gründer, S Bockholt, G Gosheger, M Schulze… - Antibiotics, 2023 - mdpi.com
Background: Increasing antibiotic resistance has been reported as an issue in the systemic
treatment of periprosthetic joint infection (PJI). Linezolid offers the advantages of high oral …