Bioanalytical applications of isothermal nucleic acid amplification techniques

H Deng, Z Gao - Analytica chimica acta, 2015 - Elsevier
The most popular in vitro nucleic acid amplification techniques like polymerase chain
reaction (PCR) including real-time PCR are costly and require thermocycling, rendering …

Thioflavin T as a fluorescence probe for biosensing applications

FY Khusbu, X Zhou, H Chen, C Ma, K Wang - TrAC Trends in Analytical …, 2018 - Elsevier
Thioflavin T (ThT), a water-soluble fluorescence probe and the conventional dye for the
detection of amyloid fibrils has recently been demonstrated to recognize and bind nucleic …

Real-time detection of isothermal amplification reactions with thermostable catalytic hairpin assembly

Y Jiang, B Li, JN Milligan, S Bhadra… - Journal of the American …, 2013 - ACS Publications
Catalytic hairpin assembly (CHA) is an enzyme-free amplification method that has
previously proven useful in amplifying and transducing signals at the terminus of nucleic …

Exponential strand-displacement amplification for detection of microRNAs

C Shi, Q Liu, C Ma, W Zhong - Analytical chemistry, 2014 - ACS Publications
MicroRNAs (miRNAs) are promising targets for disease diagnosis. However, miRNA
detection requires rapid, sensitive, and selective detection to be effective as a diagnostic …

A rolling circle amplification-based DNA machine for miRNA screening coupling catalytic hairpin assembly with DNAzyme formation

J Zhuang, W Lai, G Chen, D Tang - Chemical communications, 2014 - pubs.rsc.org
A rolling circle amplification-based DNA machine for miRNA screening coupling catalytic
hairpin assembly with DNAzyme formation - Chemical Communications (RSC Publishing) …

Hairpin DNA-templated silver nanoclusters as novel beacons in strand displacement amplification for microRNA detection

J Zhang, C Li, X Zhi, GA Ramón, Y Liu… - Analytical …, 2016 - ACS Publications
MicroRNA (miRNA) biomarkers display great potential for cancer diagnosis and prognosis.
The development of rapid and specific methods for miRNA detection has become a hotspot …

Isothermal nucleic acid amplification technology for rapid detection of virus

Z Wei, X Wang, H Feng, F Ji, D Bai… - Critical Reviews in …, 2023 - Taylor & Francis
While the research field and industrial market of in vitro diagnosis (IVD) thrived during and
post the COVID-19 pandemic, the development of isothermal nucleic acid amplification test …

Systematic review and meta‐analysis: Circulating miRNAs for diagnosis of hepatocellular carcinoma

JT Huang, SM Liu, H Ma, Y Yang… - Journal of cellular …, 2016 - Wiley Online Library
Because early‐stage hepatocellular carcinoma (HCC) is difficult to diagnose using the
existing techniques, identifying better biomarkers would likely improve the patients' …

Target‐Triggered Assembly of Nanogap Antennas to Enhance the Fluorescence of Single Molecules and Their Application in MicroRNA Detection

M Peng, F Sun, N Na, J Ouyang - Small, 2020 - Wiley Online Library
Nanogap antennas are plasmonic nanostructures with a strong electromagnetic field
generated at the gap region of two neighboring particles owing to the coupling of the …

Strand displacement amplification reaction on quantum dot-encoded silica bead for visual detection of multiplex MicroRNAs

X Qu, H Jin, Y Liu, Q Sun - Analytical chemistry, 2018 - ACS Publications
The combination of microbead array, isothermal amplification, and molecular signaling
enables the continuous development of next-generation molecular diagnostic techniques …