Non-human primate models of focal cortical ischemia for neuronal replacement therapy

J Mu, P Hao, H Duan, W Zhao… - Journal of Cerebral …, 2023 - journals.sagepub.com
Despite the high prevalence, stroke remains incurable due to the limited regeneration
capacity in the central nervous system. Neuronal replacement strategies are highly diverse …

Safety and efficacy of low-cost alternative urokinase in acute ischemic stroke: A systematic review and meta-analysis

S Kharel, G Nepal, PR Joshi, JK Yadav… - Journal of Clinical …, 2022 - Elsevier
Introduction Use of intravenous thrombolysis (IVT) for treatment of acute ischemic stroke
(AIS) varies greatly between countries, ranging from 10% to 15% in high-income countries to …

In Vitro Assessment of Protamine Toxicity with Neural Cells, Its Therapeutic Potential to Counter Chondroitin Sulfate Mediated Neuron Inhibition, and Its Effects on …

DW Nelson, JL Funnell, CH Cheung… - Advanced …, 2024 - Wiley Online Library
Multiple therapies have been studied to ameliorate the neuroinhibitory cues present after
traumatic injury to the central nervous system. Two previous in vitro studies have …

Resveratrol regulates paracrine function of cardiac microvascular endothelial cells under hypoxia/reoxygenation condition

H Cui, Y Yang, X Li, W Zong, Q Li - Die Pharmazie-An …, 2022 - ingentaconnect.com
The secreted factors from cardiac microvascular endothelial cells (CMECs) regulate the
physiological activity of adjacent tissues and could be modulated by myocardial …

Urokinase-Type Plasminogen Activator Triggers Wingless/Int1-Independent Phosphorylation of the Low-Density Lipoprotein Receptor-Related Protein-6 in Cerebral …

A Diaz, C Martin-Jimenez, Y Woo… - Journal of …, 2022 - content.iospress.com
Background: Urokinase-type plasminogen activator (uPA) is a serine proteinase found in
excitatory synapses located in the II/III and V cortical layers. The synaptic release of uPA …