Computer-aided engineering of lipases solvent tolerance enhanced their applications in sugar esters synthesis: State of the art

Y Qi, M Chen, T Jin, W Chong, Z Zhang, B Nian… - Trends in Food Science & …, 2024 - Elsevier
Abstract Background Sugar esters (SEs) are non-ionic amphiphilic surfactants that possess
excellent emulsifying properties, and consequently have potential applications in the food …

Material-specific binding peptides empower sustainable innovations in plant health, biocatalysis, medicine and microplastic quantification

M Mao, L Ahrens, J Luka, F Contreras… - Chemical Society …, 2024 - pubs.rsc.org
Material-binding peptides (MBPs) have emerged as a diverse and innovation-enabling class
of peptides in applications such as plant-/human health, immobilization of catalysts …

Corner Engineering: Tailoring Enzymes for Enhanced Resistance and Thermostability in Deep Eutectic Solvents

X Wang, Y Sheng, H Cui, J Qiao, Y Song… - Angewandte …, 2024 - Wiley Online Library
Deep eutectic solvents (DESs), heralded for their synthesis simplicity, economic viability,
and reduced volatility and flammability, have found increasing application in biocatalysis …

Engineering all-round cellulase for bioethanol production

M Wang, H Cui, C Gu, A Li, J Qiao… - ACS Synthetic …, 2023 - ACS Publications
One strategy to decrease both the consumption of crude oil and environmental damage is
through the production of bioethanol from biomass. Cellulolytic enzyme stability and …

How Does Surface Charge Engineering of Bacillus subtilis Lipase A Improve Ionic Liquid Resistance? Lessons Learned from Molecular Dynamics Simulations

S Pramanik, H Cui, GV Dhoke, CB Yildiz… - ACS Sustainable …, 2022 - ACS Publications
Biocatalysis in ionic liquids (ILs) gained substantial interest due to solvent properties of the
ILs, such as near-zero vapor pressure, high thermal stability, and wide tunability. Enzymes …

Enzyme Hydration: How to Retain Resistance in Ionic Liquids

H Cui, L Zhang, CB Yildiz, L Eltoukhy… - ACS Sustainable …, 2022 - ACS Publications
Application of ionic liquids (ILs) as media in biocatalysis has enormous potential for
synthesizing valuable compounds and bulk products in pharmaceuticals and bioenergy due …

Enhancing the organic solvent resistance of ω‐amine transaminase for enantioselective synthesis of (R)‐(+)‐1(1‐naphthyl)‐ethylamine

CN Wang, S Qiu, FF Fan, CJ Lyu, S Hu… - Biotechnology …, 2023 - Wiley Online Library
Background Biocatalysis in high‐concentration organic solvents has been applied to
produce various industrial products with many advantages. However, using enzymes in …

Surface engineering of cyclodextrin glycosyltransferase reveals structural compactness and rigidity responsible for enhanced organic solvents resistance

R Han, Y Jiang, S Liu, Y Ji, U Schwaneberg, Y Ni - Molecular Catalysis, 2023 - Elsevier
Cyclodextrin glycosyltransferase (CGTase) is a preferable biocatalyst for production of
cyclodextrin and phenols glycosylated derivatives due to its cost-effective donors and broad …

Engineering diaryl alcohol dehydrogenase KpADH reveals importance of retaining hydration shell in organic solvent tolerance

L Zhang, W Dai, S Rong, U Schwaneberg… - Protein …, 2024 - Wiley Online Library
Alcohol dehydrogenases (ADHs) are synthetically important biocatalysts for the asymmetric
synthesis of chiral alcohols. The catalytic performance of ADHs in the presence of organic …

Enrichment of EPA and DHA in glycerides by selective enzymatic ethanolysis

J Yu, Y Fu, X Tang, W Bao, Z Li, X Wang, X Wang - Food Chemistry, 2025 - Elsevier
It has been reported that eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in
glycerides have various biological functions. This study presents an effective method for …