The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …

Macrophages are primarily known as phagocytic innate immune cells, but are, in fact, highly
dynamic multi-taskers that interact with many different tissue types and have regulatory roles …

Diabetic wound healing is affected by insufficient angiogenesis, oxidative damage, and
bacterial infection, resulting in a delayed healing process. There is an urgent need to design …

Eicosanoids are lipid-based signaling molecules that play a unique role in innate immune
responses. The multiple types of eicosanoids, such as prostaglandins (PGs) and …

Leukotrienes are biologically active eicosanoid lipid mediators that originate from oxidative
metabolism of arachidonic acid. Biosynthesis of leukotrienes involves a set of soluble and …

Most existing expression quantitative trait locus (eQTL) mapping studies have been focused
on individuals of European ancestry and are underrepresented in other populations …

Diabetes caused wound healing delay is attributed to the enhanced and prolonged
inflammation, which is always induced by a large amount of inflammatory mediators …

Abstract 17β-estradiol (E2) is an important regulator of energy homeostasis and glucose
metabolism, thus making it a potential target for preventing or treating metabolic disorders …

Wound healing is an important process in the human body to protect against external
threats. A dysregulation at any stage of the wound healing process may result in the …

Introduction Macrophages are central cells in mediating the inflammatory response.
Objective and Methods We evaluated the effect of high glucose conditions on the …