Tissue regeneration from transplanted mesenchymal stromal cells (MSC) either through
transdifferentiation or cell fusion was originally proposed as the principal mechanism …

Mesenchymal stem cells (MSCs) are a prototypical adult stem cell with capacity for self-
renewal and differentiation with a broad tissue distribution. Initially described in bone …

Animal and preliminary human studies of adult cell therapy following acute myocardial
infarction have shown an overall improvement of cardiac function. Myocardial and vascular …

Background—Experimental data suggest that bone marrow–derived cells may contribute to
the healing of myocardial infarction (MI). For this reason, we analyzed 10 patients who were …

We previously reported that intramyocardial injection of bone marrow‐derived mesenchymal
stem cells overexpressing Akt (Akt‐MSCs) inhibits ventricular remodeling and restores …

Wharton's jelly (WJ) is a gelatinous tissue within the umbilical cord that contains
myofibroblast-like stromal cells. A unique cell population of WJ that has been suggested as …

Background Myocardial regeneration via stem-cell mobilisation at the time of myocardial
infarction is known to occur, although the mechanism for stem-cell homing to infarcted tissue …

Background The benefit of reperfusion therapies for ST-elevation acute myocardial infarction
(STEMI) is limited by post-infarction left-ventricular (LV) dysfunction. Our aim was to …

Background—Bone marrow–derived stem cells are under investigation as a treatment for
ischemic heart disease. Mesenchymal stem cells (MSCs) have been used preferentially in …

Cellular replacement therapy has emerged as a novel strategy for the treatment of heart
failure. The aim of our study was to determine the fate of injected mesenchymal stem cells …