Tetrazolium compounds: synthesis and applications in medicine

CX Wei, M Bian, GH Gong - Molecules, 2015 - mdpi.com
Tetrazoles represent a class of five-membered heterocyclic compounds with polynitrogen
electron-rich planar structural features. This special structure makes tetrazole derivatives …

Current scenario of tetrazole hybrids for antibacterial activity

F Gao, J Xiao, G Huang - European journal of medicinal chemistry, 2019 - Elsevier
The incidence of invasive bacterial infections has increased remarkably over the past two
decades, which was mainly attributed to the increasing emergence of drug-resistant bacteria …

Tetrazole hybrids with potential anticancer activity

J Zhang, S Wang, Y Ba, Z Xu - European journal of medicinal chemistry, 2019 - Elsevier
Cancer is one of the main causes of death throughout the world. The anticancer agents are
indispensable for the treatment of various cancers, but most of them currently on the market …

New antifungal agents with azole moieties

MM Teixeira, DT Carvalho, E Sousa, E Pinto - Pharmaceuticals, 2022 - mdpi.com
Fungal conditions affect a multitude of people worldwide, leading to increased
hospitalization and mortality rates, and the need for novel antifungals is emerging with the …

Tetrazole hybrids and their antifungal activities

SQ Wang, YF Wang, Z Xu - European journal of medicinal chemistry, 2019 - Elsevier
Fungi, which can cause serious infections, results in more than 1.35 million deaths annually
throughout the world. Azole antifungal drugs which could inhibit the enzyme lanosterol 14α …

Quinazolines annelated at the N (3)-C (4) bond: synthesis and biological activity

EV Nosova, GN Lipunova, YV Permyakova… - European Journal of …, 2024 - Elsevier
This review covers article and patent data obtained mostly within the period 2013− 2023 on
the synthesis and biological activity of quinazolines [c]-annelated by five-and six-membered …

Facile Synthesis of 7-Aryl-benzo [h] tetrazolo [5, 1-b] quinazoline-5, 6-dione fused polycyclic compounds by using a novel magnetic polyurethane catalyst

A Maleki, M Aghaei, T Kari - Polycyclic Aromatic Compounds, 2019 - Taylor & Francis
Novel Brönsted acid functionalized magnetic polymeric nanocomposite, Ba 0.5 Sr 0.5 Fe 12
O 19@ PU-SO 3 H, has been successfully synthesized and characterized by field-emission …

Micellear gold nanoparticles as delivery vehicles for dual tyrosine kinase inhibitor ZD6474 for metastatic breast cancer treatment

S Sarkar, S Konar, PN Prasad, S Rajput, BNP Kumar… - Langmuir, 2017 - ACS Publications
The therapeutic index of poorly water-soluble drugs is often hampered due to poor
pharmacokinetics, reduced blood retention, and lack of effective drug concentrations in the …

Thioethers: an overview

MI Han, ŦG Küçükgüzel - Current drug targets, 2022 - benthamdirect.com
Spreading rapidly in recent years, cancer has become one of the causes of the highest
mortality rates after cardiovascular diseases. The reason for cancer development is still not …

Application of azide-tetrazole tautomerism and arylsulfanyl group dance in the synthesis of thiosubstituted tetrazoloquinazolines

A Jeminejs, SM Goliškina, I Novosjolova… - …, 2021 - thieme-connect.com
Nucleophilic aromatic substitution reaction between 4-arylthio-2-chloroquinazolines and
NaN 3 takes place with an unusual sulfanyl group dance and leads to the formation of 5 …