[HTML][HTML] Schwann cell functions in peripheral nerve development and repair
M Bosch-Queralt, R Fledrich, RM Stassart - Neurobiology of disease, 2023 - Elsevier
The glial cell of the peripheral nervous system (PNS), the Schwann cell (SC), counts among
the most multifaceted cells of the body. During development, SCs secure neuronal survival …
the most multifaceted cells of the body. During development, SCs secure neuronal survival …
Harnessing polymer-derived drug delivery systems for combating inflammatory bowel disease
Y Pu, X Fan, Z Zhang, Z Guo, Q Pan, W Gao… - Journal of Controlled …, 2023 - Elsevier
The inflammatory bowel disease (IBD) is incurable, chronic, recrudescent disorders in the
inflamed intestines. Current clinic treatments are challenged by systemic exposure-induced …
inflamed intestines. Current clinic treatments are challenged by systemic exposure-induced …
Role of the CCL2-CCR2 axis in cardiovascular disease: Pathogenesis and clinical implications
H Zhang, K Yang, F Chen, Q Liu, J Ni, W Cao… - Frontiers in …, 2022 - frontiersin.org
The CCL2-CCR2 axis is one of the major chemokine signaling pathways that has received
special attention because of its function in the development and progression of …
special attention because of its function in the development and progression of …
Neuroimmune interactions in the intestine
A Wallrapp, IM Chiu - Annual Review of Immunology, 2024 - annualreviews.org
Recent advances have contributed to a mechanistic understanding of neuroimmune
interactions in the intestine and revealed an essential role of this cross talk for gut …
interactions in the intestine and revealed an essential role of this cross talk for gut …
Immune-epithelial cross talk in regeneration and repair
L Guenin-Mace, P Konieczny… - Annual review of …, 2023 - annualreviews.org
The epithelial tissues that line our body, such as the skin and gut, have remarkable
regenerative prowess and continually renew throughout our lifetimes. Owing to their barrier …
regenerative prowess and continually renew throughout our lifetimes. Owing to their barrier …
A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia
A Laddach, SH Chng, R Lasrado, F Progatzky… - Nature …, 2023 - nature.com
Glial cells have been proposed as a source of neural progenitors, but the mechanisms
underpinning the neurogenic potential of adult glia are not known. Using single cell …
underpinning the neurogenic potential of adult glia are not known. Using single cell …
Adrenergic nerves regulate intestinal regeneration through IL-22 signaling from type 3 innate lymphoid cells
The intestinal epithelium has high intrinsic turnover rate, and the precise renewal of the
epithelium is dependent on the microenvironment. The intestine is innervated by a dense …
epithelium is dependent on the microenvironment. The intestine is innervated by a dense …
[HTML][HTML] Tissue-specific immunity in helminth infections
F Vacca, G Le Gros - Mucosal immunology, 2022 - Elsevier
A characteristic feature of host responses to helminth infections is the development of
profound systemic and tissue-localised Type 2 immune responses that play critical roles in …
profound systemic and tissue-localised Type 2 immune responses that play critical roles in …
The role of cellular and molecular neuroimmune crosstalk in gut immunity
The gastrointestinal tract is densely innervated by the peripheral nervous system and
populated by the immune system. These two systems critically coordinate the sensations of …
populated by the immune system. These two systems critically coordinate the sensations of …
[HTML][HTML] The role of enteric glia in intestinal immunity
F Progatzky, V Pachnis - Current Opinion in Immunology, 2022 - Elsevier
Highlights•Enteric glial cells (EGCs) are required for maintenance of gut tissue
homeostasis.•GFAP+ EGCs regulate the health of the intestinal epithelial barrier.•EGCs …
homeostasis.•GFAP+ EGCs regulate the health of the intestinal epithelial barrier.•EGCs …