An introduction to the endogenous cannabinoid system
The endocannabinoid system (ECS) is a widespread neuromodulatory system that plays
important roles in central nervous system development, synaptic plasticity, and the response …
important roles in central nervous system development, synaptic plasticity, and the response …
Exercise suppresses neuroinflammation for alleviating Alzheimer's disease
M Wang, H Zhang, J Liang, J Huang… - Journal of …, 2023 - Springer
Alzheimer's disease (AD) is a chronic neurodegenerative disease, with the characteristics of
neurofibrillary tangle (NFT) and senile plaque (SP) formation. Although great progresses …
neurofibrillary tangle (NFT) and senile plaque (SP) formation. Although great progresses …
The CB2 receptor and its role as a regulator of inflammation
C Turcotte, MR Blanchet, M Laviolette… - Cellular and Molecular …, 2016 - Springer
The CB 2 receptor is the peripheral receptor for cannabinoids. It is mainly expressed in
immune tissues, highlighting the possibility that the endocannabinoid system has an …
immune tissues, highlighting the possibility that the endocannabinoid system has an …
Alternatively activated microglia and macrophages in the central nervous system
R Franco, D Fernández-Suárez - Progress in neurobiology, 2015 - Elsevier
Macrophages are important players in the fight against viral, bacterial, fungal and parasitic
infections. From a resting state they may undertake two activation pathways, the classical …
infections. From a resting state they may undertake two activation pathways, the classical …
THC and CBD: Similarities and differences between siblings
N Stella - Neuron, 2023 - cell.com
Summary Δ 9-tetrahydrocannabinol (THC) and its sibling, cannabidiol (CBD), are produced
by the same Cannabis plant and have similar chemical structures but differ dramatically in …
by the same Cannabis plant and have similar chemical structures but differ dramatically in …
[HTML][HTML] Review of the neurological benefits of phytocannabinoids
J Maroon, J Bost - Surgical neurology international, 2018 - ncbi.nlm.nih.gov
Background: Numerous physical, psychological, and emotional benefits have been
attributed to marijuana since its first reported use in 2,600 BC in a Chinese pharmacopoeia …
attributed to marijuana since its first reported use in 2,600 BC in a Chinese pharmacopoeia …
Targeting microglial activation states as a therapeutic avenue in Parkinson's disease
SR Subramaniam, HJ Federoff - Frontiers in aging neuroscience, 2017 - frontiersin.org
Parkinson's disease (PD) is a chronic and progressive disorder characterized
neuropathologically by loss of dopamine neurons in the substantia nigra, intracellular …
neuropathologically by loss of dopamine neurons in the substantia nigra, intracellular …
Physiology of microglia
H Kettenmann, UK Hanisch, M Noda… - Physiological …, 2011 - journals.physiology.org
Microglial cells are the resident macrophages in the central nervous system. These cells of
mesodermal/mesenchymal origin migrate into all regions of the central nervous system …
mesodermal/mesenchymal origin migrate into all regions of the central nervous system …
CB2 receptor in microglia: the guardian of self-control
JA Komorowska-Müller, AC Schmöle - International journal of molecular …, 2020 - mdpi.com
Microglia are key to maintaining the homeostasis of the brain. These immune cells of the
brain can be our biggest ally in fighting infections, but can worsen pathology or hinder …
brain can be our biggest ally in fighting infections, but can worsen pathology or hinder …
Glutamatergic mechanisms associated with seizures and epilepsy
M Barker-Haliski, HS White - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Epilepsy is broadly characterized by aberrant neuronal excitability. Glutamate is the
predominant excitatory neurotransmitter in the adult mammalian brain; thus, much of past …
predominant excitatory neurotransmitter in the adult mammalian brain; thus, much of past …