Characterizing extracellular vesicles and their diverse RNA contents

EM Veziroglu, GI Mias - Frontiers in Genetics, 2020 - frontiersin.org
Cells release nanometer-scale, lipid bilayer-enclosed biomolecular packages (extracellular
vesicles; EVs) into their surrounding environment. EVs are hypothesized to be intercellular …

The extracellular RNA communication consortium: establishing foundational knowledge and technologies for extracellular RNA research

S Das, AB Abdel-Mageed, C Adamidi, PD Adelson… - Cell, 2019 - cell.com
The Extracellular RNA Communication Consortium (ERCC) was launched to accelerate
progress in the new field of extracellular RNA (exRNA) biology and to establish whether …

[HTML][HTML] exRNA atlas analysis reveals distinct extracellular RNA cargo types and their carriers present across human biofluids

OD Murillo, W Thistlethwaite, J Rozowsky… - Cell, 2019 - cell.com
To develop a map of cell-cell communication mediated by extracellular RNA (exRNA), the
NIH Extracellular RNA Communication Consortium created the exRNA Atlas resource …

Small RNA sequencing across diverse biofluids identifies optimal methods for exRNA isolation

S Srinivasan, A Yeri, PS Cheah, A Chung, K Danielson… - Cell, 2019 - cell.com
Poor reproducibility within and across studies arising from lack of knowledge regarding the
performance of extracellular RNA (exRNA) isolation methods has hindered progress in the …

Metabolic architecture of acute exercise response in middle-aged adults in the community

M Nayor, RV Shah, PE Miller, JB Blodgett, M Tanguay… - Circulation, 2020 - Am Heart Assoc
Background: Whereas regular exercise is associated with lower risk of cardiovascular
disease and mortality, mechanisms of exercise-mediated health benefits remain less clear …

[HTML][HTML] Non-coding RNAs in exercise immunology: A systematic review

M Kotewitsch, M Heimer, B Schmitz… - Journal of Sport and Health …, 2024 - Elsevier
Regular physical exercise has been recognized as a potent modulator of immune function,
with its effects including enhanced immune surveillance, reduced inflammation, and …

Circulating Y-RNAs in extracellular vesicles and ribonucleoprotein complexes; implications for the immune system

TAP Driedonks, ENM Nolte-'t Hoen - Frontiers in immunology, 2019 - frontiersin.org
The exchange of extracellular vesicles (EV) between immune cells plays a role in various
immune regulatory processes. EV are nano-sized lipid bilayer-enclosed structures that …

Sedentary and trained older men have distinct circulating exosomal microRNA profiles at baseline and in response to acute exercise

VD Nair, Y Ge, S Li, H Pincas, N Jain… - Frontiers in …, 2020 - frontiersin.org
Exercise has multi-systemic benefits and attenuates the physiological impairments
associated with aging. Emerging evidence suggests that circulating exosomes mediate …

Aerobic exercise training mitigates tumor growth and cancer-induced splenomegaly through modulation of non-platelet platelet factor 4 expression

GC Tobias, JLP Gomes, LG Fernandes, VA Voltarelli… - Scientific Reports, 2023 - nature.com
Exercise training reduces the incidence of several cancers, but the mechanisms underlying
these effects are not fully understood. Exercise training can affect the spleen function, which …

Differential effects of APOE genotype on MicroRNA cargo of cerebrospinal fluid extracellular vesicles in females with Alzheimer's disease compared to males

US Sandau, TJ McFarland, SJ Smith… - Frontiers in Cell and …, 2022 - frontiersin.org
Multiple biological factors, including age, sex, and genetics, influence Alzheimer's disease
(AD) risk. Of the 6.2 million Americans living with Alzheimer's dementia in 2021, 3.8 million …