A new dawn for eosinophils in the tumour microenvironment
Eosinophils are evolutionarily conserved, pleotropic cells that display key effector functions
in allergic diseases, such as asthma. Nonetheless, eosinophils infiltrate multiple tumours …
in allergic diseases, such as asthma. Nonetheless, eosinophils infiltrate multiple tumours …
Chimeric antigen receptor T (CAR‐T) cells: Novel cell therapy for hematological malignancies
S Abbasi, MA Totmaj, M Abbasi, S Hajazimian… - Cancer …, 2023 - Wiley Online Library
Over the last decade, the emergence of several novel therapeutic approaches has changed
the therapeutic perspective of human malignancies. Adoptive immunotherapy through …
the therapeutic perspective of human malignancies. Adoptive immunotherapy through …
Guideline for the investigation and management of eosinophilia
The guideline group was selected to be representative of UK-based medical experts with an
interest in myeloproliferative neoplasms and eosinophilia. PubMed and EMBASE were …
interest in myeloproliferative neoplasms and eosinophilia. PubMed and EMBASE were …
Multiparameter flow cytometry in the evaluation of myelodysplasia: analytical issues: recommendations from the European Leukemianet/International Myelodysplastic …
A Porwit, MC Béné, C Duetz, S Matarraz… - Cytometry Part B …, 2023 - Wiley Online Library
Multiparameter flow cytometry (MFC) is one of the essential ancillary methods in bone
marrow (BM) investigation of patients with cytopenia and suspected myelodysplastic …
marrow (BM) investigation of patients with cytopenia and suspected myelodysplastic …
Eosinophils in the tumor microenvironment
F Mattei, S Andreone, G Marone… - … Cells–Part B, 2020 - Springer
Eosinophils are rare blood-circulating and tissue-infiltrating immune cells studied for
decades in the context of allergic diseases and parasitic infections. Eosinophils can secrete …
decades in the context of allergic diseases and parasitic infections. Eosinophils can secrete …
Hypereosinophilia management in patients with type 2 chronic rhinosinusitis treated with dupilumab: preliminary results
A Vinciguerra, A Rampi, MR Yacoub, M Tresoldi… - European Archives of …, 2022 - Springer
Purpose Biological therapies are gaining relevance in the management of CRSwNP with
few adverse events reported. Among these, dupilumab, an anti-IL4-Ra monoclonal antibody …
few adverse events reported. Among these, dupilumab, an anti-IL4-Ra monoclonal antibody …
Pretreatment eosinophil counts as a predictive biomarker in non‐small cell lung cancer patients treated with immune checkpoint inhibitors
E Takeuchi, K Kondo, Y Okano, S Ichihara… - Thoracic …, 2023 - Wiley Online Library
Background The peripheral blood eosinophil count prior to treatment has potential as a
predictive biomarker for a beneficial clinical response to cancer immunotherapies …
predictive biomarker for a beneficial clinical response to cancer immunotherapies …
White cell counts in relation to mortality in a general population of cohort study in the Netherlands: a mediating effect or not?
Background White cell count (WCC) is a clinical marker of inflammation. Data are limited
regarding the association of total and differential WCC with risk of mortality, and its role …
regarding the association of total and differential WCC with risk of mortality, and its role …
Identification of autofluorescent cells in human angioimmunoblastic T-cell lymphoma
I Buchwalow, D Atiakshin, V Samoilova… - Histochemistry and Cell …, 2018 - Springer
Endogenous cell autofluorescence is a common nuisance that complicates the use of
fluorescence microscopy. When using fluorescence-labeled antibodies for specific cell …
fluorescence microscopy. When using fluorescence-labeled antibodies for specific cell …
[HTML][HTML] A novel deletion mutation in KMT2A identified in a child with ID/DD and blood eosinophilia
H Zhang, B Xiang, H Chen, X Chen, T Cai - BMC medical genetics, 2019 - Springer
Abstract Background The KMT2A gene encoded lysine methyltransferase plays an essential
role in regulating gene expression during early development and hematopoiesis. To date …
role in regulating gene expression during early development and hematopoiesis. To date …