High‐throughput metabolomics by 1D NMR
Metabolomics deals with the whole ensemble of metabolites (the metabolome). As one of
the‐omic sciences, it relates to biology, physiology, pathology and medicine; but metabolites …
the‐omic sciences, it relates to biology, physiology, pathology and medicine; but metabolites …
From correlation to causation: analysis of metabolomics data using systems biology approaches
Introduction Metabolomics is a well-established tool in systems biology, especially in the top–
down approach. Metabolomics experiments often results in discovery studies that provide …
down approach. Metabolomics experiments often results in discovery studies that provide …
Comorbidity-associated glutamine deficiency is a predisposition to severe COVID-19
T Matsuyama, SK Yoshinaga, K Shibue… - Cell Death & …, 2021 - nature.com
SARS-CoV-2 vaccinations have greatly reduced COVID-19 cases, but we must continue to
develop our understanding of the nature of the disease and its effects on human immunity …
develop our understanding of the nature of the disease and its effects on human immunity …
[HTML][HTML] Uniqueness of the NMR approach to metabolomics
NMR measures a relatively small portion of the human metabolome, which roughly
corresponds to all free small molecules present in concentrations≥ 1 μM. However, the …
corresponds to all free small molecules present in concentrations≥ 1 μM. However, the …
Sex as an important factor in nanomedicine
Nanomedicine has demonstrated substantial potential to improve the quality and efficacy of
healthcare systems. Although the promise of nanomedicine to transform conventional …
healthcare systems. Although the promise of nanomedicine to transform conventional …
Ambient PM2. 5 species and ultrafine particle exposure and their differential metabolomic signatures
Background The metabolomic signatures of short-and long-term exposure to PM 2.5 have
been reported and linked to inflammation and oxidative stress. However, little is known …
been reported and linked to inflammation and oxidative stress. However, little is known …
[HTML][HTML] A validated multi-matrix platform for metabolomic fingerprinting of human urine, feces and plasma using ultra-high performance liquid-chromatography …
E De Paepe, L Van Meulebroek, C Rombouts… - Analytica chimica …, 2018 - Elsevier
In recent years, metabolomics has surfaced as an innovative research strategy in human
metabolism, whereby selection of the biological matrix and its inherent metabolome is of …
metabolism, whereby selection of the biological matrix and its inherent metabolome is of …
Untargeted urinary metabolomics for bladder cancer biomarker screening with ultrahigh-resolution mass spectrometry
Bladder cancer (BC) is a common urological malignancy with a high probability of death and
recurrence. Cystoscopy is used as a routine examination for diagnosis and following patient …
recurrence. Cystoscopy is used as a routine examination for diagnosis and following patient …
Age, sex, body mass index, diet and menopause related metabolites in a large homogeneous alpine cohort
V Verri Hernandes, N Dordevic, EM Hantikainen… - Metabolites, 2022 - mdpi.com
Metabolomics in human serum samples provide a snapshot of the current metabolic state of
an individuum. Metabolite concentrations are influenced by both genetic and environmental …
an individuum. Metabolite concentrations are influenced by both genetic and environmental …
Metabolite and lipoprotein profiles reveal sex-related oxidative stress imbalance in de novo drug-naive Parkinson's disease patients
Parkinson's disease (PD) is the neurological disorder showing the greatest rise in
prevalence from 1990 to 2016. Despite clinical definition criteria and a tremendous effort to …
prevalence from 1990 to 2016. Despite clinical definition criteria and a tremendous effort to …