Diabetic cardiomyopathy: Early diagnostic biomarkers, pathogenetic mechanisms, and therapeutic interventions
JL Huo, Q Feng, S Pan, WJ Fu, Z Liu, Z Liu - Cell death discovery, 2023 - nature.com
Diabetic cardiomyopathy (DCM) mainly refers to myocardial metabolic dysfunction caused
by high glucose, and hyperglycemia is an independent risk factor for cardiac function in the …
by high glucose, and hyperglycemia is an independent risk factor for cardiac function in the …
Animal models of heart failure with preserved ejection fraction (HFpEF): from metabolic pathobiology to drug discovery
S Gao, X Liu, T Li, L Chen, Y Feng, Y Wang… - Acta Pharmacologica …, 2024 - nature.com
Heart failure (HF) with preserved ejection fraction (HFpEF) is currently a preeminent
challenge for cardiovascular medicine. It has a poor prognosis, increasing mortality, and is …
challenge for cardiovascular medicine. It has a poor prognosis, increasing mortality, and is …
[HTML][HTML] Novel insights into the role of mitochondria in diabetic cardiomyopathy: molecular mechanisms and potential treatments
F Zhi, Q Zhang, L Liu, X Chang, H Xu - Cell Stress and Chaperones, 2023 - Elsevier
Diabetic cardiomyopathy describes decreased myocardial function in diabetic patients in the
absence of other heart diseases such as myocardial ischemia and hypertension. Recent …
absence of other heart diseases such as myocardial ischemia and hypertension. Recent …
Mitochondria-associated endoplasmic reticulum membrane (MAM): a dark horse for diabetic cardiomyopathy treatment
Y Liu, JL Huo, K Ren, S Pan, H Liu, Y Zheng… - Cell Death …, 2024 - nature.com
Diabetic cardiomyopathy (DCM), an important complication of diabetes mellitus (DM), is one
of the most serious chronic heart diseases and has become a major cause of heart failure …
of the most serious chronic heart diseases and has become a major cause of heart failure …
Using mass spectrometry imaging to visualize age-related subcellular disruption
Metabolic homeostasis balances the production and consumption of energetic molecules to
maintain active, healthy cells. Cellular stress, which disrupts metabolism and leads to the …
maintain active, healthy cells. Cellular stress, which disrupts metabolism and leads to the …
Ginsenoside Rg1 improved diabetes through regulating the intestinal microbiota in high‐fat diet and streptozotocin‐induced type 2 diabetes rats
M Peng, L Wang, H Su, L Zhang, Y Yang… - Journal of Food …, 2022 - Wiley Online Library
Ginsenoside Rg1 is the active ingredient of the plant named genus Panax (ginseng), which
exhibited significant bioactivities, including anti‐inflammatory, antioxidation, and anti …
exhibited significant bioactivities, including anti‐inflammatory, antioxidation, and anti …
[HTML][HTML] Molecular Basis of Cardiomyopathies in Type 2 Diabetes
S Giardinelli, G Meliota, D Mentino, G D'Amato… - International Journal of …, 2024 - mdpi.com
Diabetic cardiomyopathy (DbCM) is a common complication in individuals with type 2
diabetes mellitus (T2DM), and its exact pathogenesis is still debated. It was hypothesized …
diabetes mellitus (T2DM), and its exact pathogenesis is still debated. It was hypothesized …
Myocardial metabolic reprogramming in HFpEF
Z Zhang, M Sun, W Jiang, L Yu, C Zhang… - Journal of Cardiovascular …, 2024 - Springer
Heart failure (HF) caused by structural or functional cardiac abnormalities is a significant
cause of morbidity and mortality worldwide. While HF with reduced ejection fraction (HErEF) …
cause of morbidity and mortality worldwide. While HF with reduced ejection fraction (HErEF) …
[HTML][HTML] Broadening horizons: the contribution of mitochondria-associated endoplasmic reticulum membrane (MAM) dysfunction in diabetic kidney disease
Y Liu, Y Qiao, S Pan, J Chen, Z Mao… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Diabetic kidney disease (DKD) is a global health issue that presents a complex
pathogenesis and limited treatment options. To provide guidance for precise therapies, it is …
pathogenesis and limited treatment options. To provide guidance for precise therapies, it is …
Moderate-Intensity and High-Intensity Interval Exercise Training Offer Equal Cardioprotection, with Different Mechanisms, during the Development of Type 2 Diabetes …
S D'Haese, L Claes, I de Laat, S Van Campenhout… - Nutrients, 2024 - mdpi.com
Endurance exercise training is a promising cardioprotective strategy in type 2 diabetes
mellitus (T2DM), but the impact of its intensity is not clear. We aimed to investigate whether …
mellitus (T2DM), but the impact of its intensity is not clear. We aimed to investigate whether …