Heparin has been recognized as a valuable anticoagulant and antithrombotic for several
decades and is still widely used in clinical practice for a variety of indications. The …

Protein and lipid glycosylation is no longer considered as a topic whose appeal is restricted
to a limited number of analytical experts perseveringly pursuing the comprehensive …

The adhesive interactions of endothelial cells with each other and the adhesion receptors
that mediate these interactions are probably of fundamental importance to the process of …

Human embryonic stem (ES) cells are undifferentiated, pluripotent cells that can be
maintained indefinitely in culture. Here we demonstrate that human ES cells differentiate to …

ABSTRACT Cbfa2 (AML1) encodes the DNA-binding subunit of a transcription factor in the
small family of core-binding factors (CBFs). Cbfa2 is required for the differentiation of all …

Hematopoiesis is established from circulating blood stem cells that seed the embryonic
rudiments of blood-forming tissues, a basic notion in developmental hematology. However …

Heparan sulfate proteoglycans are ubiquitously found at the cell surface and extracellular
matrix in all the animal species. This review will focus on the structural characteristics of the …

The glycosaminoglycan heparin has been used in the clinic as an anticoagulant for more
than 50 years. A fully characterized sequence in native heparin is known to be responsible …

Among vascular cell adbesio, molecules, platelet-endothelial cell adhesion molecule
(PECAM-1/CD31) has the distinctive feature of being expressed on several of the major cell …

Neutrophil emigration in the lung differs substantially from that in systemic vascular beds
where extravasation occurs primarily through postcapillary venules. Migration into the …