Compared with conventional chemotherapy and targeted therapy, immunotherapy has
changed the treatment prospects of various solid tumors and has recently become the main …

Colorectal cancer (CRC) has the second highest mortality rate among all cancers
worldwide. Surgery, chemotherapy, radiotherapy, molecular targeting and other treatment …

Cancer vaccines are designed to promote tumor specific immune responses, particularly
cytotoxic CD8 positive T cells that are specific to tumor antigens. The earliest vaccines …

Tumors evade the immune system though a myriad of mechanisms. Using checkpoint
inhibitors to help reprime T cells to recognize tumor has had great success in malignancies …

Purpose: Whole tumor lysates are promising antigen sources for dendritic cell (DC) therapy
as they contain many relevant immunogenic epitopes to help prevent tumor escape. Two …

Strong evidence supports the concept of immunosurveillance and immunoediting in
colorectal cancer. In particular, the density of T CD8+ and CD45+ lymphocyte infiltration was …

For many years, immunotherapeutic approaches for cancer held more promise than actual
clinical benefit for the majority of patients. However, several recent key advances in tumor …

Dendritic cells (DCs) occupy a central position in the immune system, orchestrating a wide
repertoire of responses that span from the development of self-tolerance to the elicitation of …

Objective: To determine whether 1 of 2 vaccines based on dendritic cells (DCs) and
poxvectors encoding CEA (carcinoembryonic antigen) and MUC1 (PANVAC) would …

Shigella sonnei is one of the major causes of shigellosis in technically advanced countries
and reports of its unprecedented increase are published from the Middle East, Latin …