[HTML][HTML] Cytokines and chemokines involved in osteoarthritis pathogenesis

V Molnar, V Matišić, I Kodvanj, R Bjelica… - International journal of …, 2021 - mdpi.com
Osteoarthritis is a common cause of disability worldwide. Although commonly referred to as
a disease of the joint cartilage, osteoarthritis affects all joint tissues equally. The …

[HTML][HTML] Knee osteoarthritis: a review of pathogenesis and state-of-the-art non-operative therapeutic considerations

D Primorac, V Molnar, E Rod, Ž Jeleč, F Čukelj… - Genes, 2020 - mdpi.com
Being the most common musculoskeletal progressive condition, osteoarthritis is an
interesting target for research. It is estimated that the prevalence of knee osteoarthritis (OA) …

[HTML][HTML] Cell therapy: types, regulation, and clinical benefits

AEH El-Kadiry, M Rafei, R Shammaa - Frontiers in Medicine, 2021 - frontiersin.org
Cell therapy practices date back to the 19th century and continue to expand on
investigational and investment grounds. Cell therapy includes stem cell-and non–stem cell …

[HTML][HTML] Immunoglobulin G glycosylation in aging and diseases

I Gudelj, G Lauc, M Pezer - Cellular Immunology, 2018 - Elsevier
Abstract The Immunoglobulin G (IgG) glycome is well known for its heterogeneity and shows
a significant degree of variation within populations. IgG glycome composition is influenced …

Exosomes derived from human urine–derived stem cells overexpressing miR-140-5p alleviate knee osteoarthritis through downregulation of VEGFA in a rat model

Y Liu, Y Zeng, HB Si, L Tang… - The American journal …, 2022 - journals.sagepub.com
Background: Knee osteoarthritis (KOA) is one of the most common chronic musculoskeletal
disorders worldwide, for which exosomes derived from stem cells may provide an effective …

[HTML][HTML] Injective mesenchymal stem cell-based treatments for knee osteoarthritis: from mechanisms of action to current clinical evidences

S Lopa, A Colombini, M Moretti… - Knee surgery, sports …, 2019 - Springer
Purpose Osteoarthritis (OA) represents a relevant social and economic burden worldwide.“
Mesenchymal stem cells” or, as recently proposed,“medicinal signaling cells”(MSCs) have …

[HTML][HTML] Osteoarthritis and stem cell therapy in humans: a systematic review

DS Jevotovsky, AR Alfonso, TA Einhorn… - Osteoarthritis and …, 2018 - Elsevier
Objective Osteoarthritis (OA) is a leading cause of disability in the world. Mesenchymal stem
cells (MSCs) have been studied to treat OA. This review was performed to systematically …

Stromal vascular fraction technologies and clinical applications

I Andia, N Maffulli, N Burgos-Alonso - Expert opinion on biological …, 2019 - Taylor & Francis
Introduction: The heterogeneous pool of cells found in the stromal vascular fraction of
adipose tissue (SVF) and the purified mesenchymal stromal/stem cells (ASCs) isolated from …

Microfragmented adipose tissue versus platelet-rich plasma for the treatment of knee osteoarthritis: a prospective randomized controlled trial at 2-year follow-up

S Zaffagnini, L Andriolo, A Boffa… - … American Journal of …, 2022 - journals.sagepub.com
Background: Intra-articular microfragmented adipose tissue (MF-AT) injections have been
proposed for the treatment of knee osteoarthritis (OA). Purpose: To compare a single …

[HTML][HTML] Comprehensive review of knee osteoarthritis pharmacological treatment and the latest professional societies' guidelines

D Primorac, V Molnar, V Matišić, D Hudetz, Ž Jeleč… - Pharmaceuticals, 2021 - mdpi.com
Osteoarthritis is the most common musculoskeletal progressive disease, with the knee as
the most commonly affected joint in the human body. While several new medications are still …