T cell subsets and functions in atherosclerosis

R Saigusa, H Winkels, K Ley - Nature Reviews Cardiology, 2020 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall and the primary
underlying cause of cardiovascular disease. Data from in vivo imaging, cell-lineage tracing …

The immunologic role of IL-17 in psoriasis and psoriatic arthritis pathogenesis

A Blauvelt, A Chiricozzi - Clinical reviews in allergy & immunology, 2018 - Springer
Psoriasis is a chronic, immune-mediated, inflammatory disease that is pathogenically driven
by proinflammatory cytokines. This article reviews the immunologic role of interleukin (IL)-17 …

Systemic inflammation and cardiovascular comorbidity in psoriasis patients: causes and consequences

WH Boehncke - Frontiers in immunology, 2018 - frontiersin.org
Psoriasis is a common inflammatory skin disease characterized by the appearance of red
scaly plaques that can affect any part of the body. High prevalence, chronicity, disfiguration …

Targeting IL-17 and TH17 cells in chronic inflammation

P Miossec, JK Kolls - Nature reviews Drug discovery, 2012 - nature.com
The key role of interleukin-17 (IL-17) and T helper 17 (TH17) cells in tissue inflammation,
autoimmunity and host defence led to the experimental targeting of these molecules in …

[HTML][HTML] Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions

BB Davidovici, N Sattar, PC Jörg, L Puig… - Journal of Investigative …, 2010 - Elsevier
Psoriasis is now classified as an immune-mediated inflammatory disease (IMID) of the skin.
It is being recognized that patients with various IMIDs, including psoriasis, are at higher risk …

Psoriasis and cardiovascular comorbidities: focusing on severe vascular events, cardiovascular risk factors and implications for treatment

SCS Hu, CCE Lan - International journal of molecular sciences, 2017 - mdpi.com
Psoriasis is a common and chronic inflammatory disease of the skin. It may impair the
physical and psychosocial function of patients and lead to decreased quality of life …

Cytokines, macrophage lipid metabolism and foam cells: implications for cardiovascular disease therapy

JE McLaren, DR Michael, TG Ashlin, DP Ramji - Progress in lipid research, 2011 - Elsevier
Cardiovascular disease is the biggest killer globally and the principal contributing factor to
the pathology is atherosclerosis; a chronic, inflammatory disorder characterized by lipid and …

IL-17 and Th17 cells in atherosclerosis: subtle and contextual roles

S Taleb, A Tedgui, Z Mallat - Arteriosclerosis, thrombosis, and …, 2015 - Am Heart Assoc
Atherosclerosis is a chronic inflammatory arterial disease driven by both innate and adaptive
immune responses to modified lipoproteins and components of the injured vascular wall …

IL-33 reduces the development of atherosclerosis

AM Miller, D Xu, DL Asquith, L Denby, Y Li… - The Journal of …, 2008 - rupress.org
Atherosclerosis is a chronic inflammatory disease of the vasculature commonly leading to
myocardial infarction and stroke. We show that IL-33, which is a novel IL-1–like cytokine that …

eNOS uncoupling in cardiovascular diseases-the role of oxidative stress and inflammation

S Karbach, P Wenzel, A Waisman… - Current …, 2014 - ingentaconnect.com
Many cardiovascular diseases and drug-induced complications are associated with-or even
based on-an imbalance between the formation of reactive oxygen and nitrogen species …