Age-associated chronic diseases require age-old medicine: role of chronic inflammation

S Prasad, B Sung, BB Aggarwal - Preventive medicine, 2012 - Elsevier
Most chronic diseases—such as cancer, cardiovascular disease (CVD), Alzheimer disease,
Parkinson disease, arthritis, diabetes and obesity—are becoming leading causes of …

Nutraceuticals, nutritional therapy, phytonutrients, and phytotherapy for improvement of human health: a perspective on plant biotechnology application

J Zhao - Recent patents on biotechnology, 2007 - ingentaconnect.com
Plants are one of the most important resources of human foods and medicines. Rapidly
increasing knowledge on nutrition, medicine, and plant biotechnology has dramatically …

Anti-inflammatory, anti-proliferative and anti-atherosclerotic effects of quercetin in human in vitro and in vivo models

R Kleemann, L Verschuren, M Morrison, S Zadelaar… - Atherosclerosis, 2011 - Elsevier
OBJECTIVE: Polyphenols such as quercetin may exert several beneficial effects, including
those resulting from anti-inflammatory activities, but their impact on cardiovascular health is …

AtMYB12 regulates caffeoyl quinic acid and flavonol synthesis in tomato: expression in fruit results in very high levels of both types of polyphenol

J Luo, E Butelli, L Hill, A Parr, R Niggeweg… - The Plant …, 2008 - Wiley Online Library
Plant polyphenolics exhibit a broad spectrum of health‐promoting effects when consumed
as part of the diet, and there is considerable interest in enhancing the levels of these …

Genetically engineered plants and foods: a scientist's analysis of the issues (Part I)

PG Lemaux - Annu. Rev. Plant Biol., 2008 - annualreviews.org
Through the use of the new tools of genetic engineering, genes can be introduced into the
same plant or animal species or into plants or animals that are not sexually compatible—the …

[PDF][PDF] A review of recent research on tomato nutrition, breeding and post-harvest technology with reference to fruit quality

HC Passam, IC Karapanos, PJ Bebeli… - The European journal of …, 2007 - Citeseer
The continued importance of tomato (Lycopersicon esculentum Mill.) as a vegetable and
salad commodity is reflected by the large volume of research on virtually all aspects of the …

[HTML][HTML] Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis

R Kleemann, L Verschuren, MJ Van Erk, Y Nikolsky… - Genome biology, 2007 - Springer
Background Increased dietary cholesterol intake is associated with atherosclerosis.
Atherosclerosis development requires a lipid and an inflammatory component. It is unclear …

Mode of inheritance of primary metabolic traits in tomato

N Schauer, Y Semel, I Balbo, M Steinfath… - The Plant …, 2008 - academic.oup.com
To evaluate components of fruit metabolic composition, we have previously metabolically
phenotyped tomato (Solanum lycopersicum) introgression lines containing segmental …

[HTML][HTML] Metabolic engineering of flavonoids in tomato (Solanum lycopersicum): the potential for metabolomics

A Bovy, E Schijlen, RD Hall - Metabolomics, 2007 - Springer
Flavonoids comprise a large and diverse group of polyphenolic plant secondary
metabolites. In plants, flavonoids play important roles in many biological processes such as …

MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated …

L Verschuren, T Kooistra, J Bernhagen… - Circulation …, 2009 - Am Heart Assoc
Chronic inflammation in white adipose tissue (WAT) is positively associated with obesity,
insulin resistance (IR) and the development of type 2 diabetes. The proinflammatory …